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Clinical Trials: Transitional & Regenerative Medicine


Source: South China Research Center for Stem Cell and Regenerative Medicine
The purpose of the present study is to evaluate the safety and exploratory efficacy of the umbilical cord mesenchymal stem cells for patients with fracture and bone nonunion. Read More
Last Updated: 22 Jun 2016
Source: Advanced Technologies and Regenerative Medicine, LLC (ATRM)
The purpose of this study is to determine the safety and effectiveness of HEALOS compared with autograft using the transforaminal lumbar interbody fusion (TLIF) method. Read More
Last Updated: 07 Feb 2011
Source: Nantes University Hospital
Articular cartilage can be the seat of many diseases including osteoarthritis and traumatic defaults. The cartilage has no intrinsic ability to repair resulting at long term in function loss in the joints. Currently available treatments are not satisfactory in the long term, the use of mesenchymal stem cells appears to be promising due to their ability to multipotency and immunomodulation properties. This project aims to determine the most appropriate source ... Read More
Last Updated: 04 Oct 2015
Source: Singapore General Hospital
To find out if a transitional care model can reduce the rate of unscheduled readmission to the Department of Internal Medicine (DIM) in SGH Read More
Last Updated: 28 Jan 2015
Source: Stanford University
We will combine an oral investigational VEGF inhibitor called papopanib which is being studied in kidney cancer will be combined with standard chemotherapy called taxol in patients with relapsed recurrent urothelial cancer. Read More
Last Updated: 07 Jul 2014
Source: Cambridge University Hospitals NHS Foundation Trust
This study aims to use tissue from deceased organ donors to investigate organ physiology, developmental biology, as well as the development of future regenerative cellular therapies. It will investigate function and immune response to stem cells as well as their generation from adult cells and generation of induced pluripotent stem cells (iPSCs). Read More
Last Updated: 12 Jul 2016
Source: Baylor College of Medicine
Transitional formulas (22 kcal/oz) are recommended for infants less than 35 weeks gestation at birth. However, few data are available related to follow-up of infants receiving these formulas who were 28-34 weeks gestation at birth. Primary hypothesis: Provision of supplemental vitamin D to a transitional formula will lead to higher serum 25-hydroxyvitamin D (25-OHD) levels and no infant with a serum 25-OHD less than 20 ng/mL when assessed at approximately ... Read More
Last Updated: 21 Jul 2016
Source: Center for Integrative Medicine, Germany
A treatment with the concept of mitochondrial medication developed by Dr Heinrich Kremer can demonstrably improve and successfully treat actual parameters of Diabetes Mellitus II as well as its risk factors. Read More
Last Updated: 14 Nov 2010
Source: South China Research Center for Stem Cell and Regenerative Medicine
The overall goal of this study is to evaluate the safety and exploratory efficacy of the injectable filler agent composed of umbilical cord mesenchymal stem cells and hyaluronic acid for the improvement of wrinkles, acne, pitting scar and so on. Read More
Last Updated: 02 Mar 2016
Source: South China Research Center for Stem Cell and Regenerative Medicine
The intent of this clinical study is to evaluate the safety of the injection composed of autologous bone marrow derived endothelial cells (BM-ECs) and platelet-rich plasma extract (PRPE) for the treatment of critical limb ischemia. Read More
Last Updated: 12 Dec 2016
Source: South China Research Center for Stem Cell and Regenerative Medicine
The purpose of this study is to investigate the efficacy and safety of transplantation of umbilical cord mesenchymal stem cells(UCMSCs) in patient with Knee cartilage damage. Read More
Last Updated: 15 May 2016
Source: South China Research Center for Stem Cell and Regenerative Medicine
The purpose of the present study is to evaluate the safety and exploratory efficacy of the medical collagen membrane with umbilical cord derived mesenchymal stem cells in the treatment of patients with skin defects. Read More
Last Updated: 30 Jan 2016
Source: Medistem Inc.
This is a 15 patient clinical trial assessing the safety and feasibility of using Endometrial Regenerative Cells (ERC) in patients with critical limb ischemia (CLI) that are not eligible for surgical or catheter-based interventions. Three doses of ERC will be examined. The hypothesis is that ERC administration will be well-tolerated and possibly induce a therapeutic benefit. Read More
Last Updated: 17 Mar 2012
Source: Fundacion Clinic per a la Recerca Biomédica
Progenitor limbo sclerocorneal cells have properties of proliferation and differentiation to corneal and conjunctival epithelium. This cells can be isolated and ex vivo expanded using cell culture technics that could permit the biological replacement of damaged ocular surface. Read More
Last Updated: 06 Dec 2012
Source: Uniformed Services University of the Health Sciences
The goal of this project is to develop a test to assess frontal lobe function using a rapid, inexpensive, objective, and standardized method, without the need for expertise in cognitive test administration. Such methods would be particularly helpful in traumatic brain injury (TBI), where objective measures are needed, and would greatly expand the capacity to make such assessments in clinical practice and research. Read More
Last Updated: 29 Dec 2015
Source: The University of Texas Health Science Center at San Antonio
Millions of teeth are saved each year by root canal therapy. Although current treatment modalities offer high levels of success for many conditions, an ideal form of therapy might consist of regenerative approaches in which diseased or necrotic pulp tissues are removed and replaced with healthy pulp tissue in order to revitalize teeth. Read More
Last Updated: 13 Sep 2012
Source: Spectrum Pharmaceuticals, Inc
The purpose of this study is to determine whether pralatrexate, given with vitamin B12 and folic acid, is effective in the treatment of advanced or metastatic bladder cancer. The study will also investigate the safety of pralatrexate with vitamin B12 and folic acid in this patient population. Additionally, this study includes the collection of blood samples to investigate the pharmacokinetics (PK) of pralatrexate in this patient population (PK is the ... Read More
Last Updated: 07 May 2013
Source: South China Research Center for Stem Cell and Regenerative Medicine
The primary purpose of this study is to evaluate the safety and the efficacy of (Human Umbilical Cord-Derived Mesenchymal Stem Cells) UCMSCs for patients with Alzheimer's disease (AD). Read More
Last Updated: 28 Jan 2016
Source: National Cancer Institute (NCI)
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Colony-stimulating factors such as filgrastim may increase the number of immune cells found in bone marrow or peripheral blood and may help a person's immune system recover from the side effects of chemotherapy. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy with gemcitabine and docetaxel plus filgrastim in ... Read More
Last Updated: 02 Dec 2013
Source: Shire Regenerative Medicine, Inc.
This study randomly assigns patients with diabetic foot ulcers to receive standard therapy (surgical debridement, saline-moistened gauze and offloading) alone or standard therapy plus Dermagraft(R). Dermagraft is a device containing live human fibroblasts grown on an absorbable Vicryl mesh. Patients are seen weekly until they heal or the 12-week treatment period is complete. Read More
Last Updated: 08 Aug 2013
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