Early prophylactic inhalation of Budesonide reduces the absolute risk of developing
bronchopulmonary dysplasia (BPD) or death in preterm infants born <28 weeks gestational age
(GA) by 10%.
To determine whether inhalation of Budesonide within 12 hours of life improves survival
without BPD at 36 weeks GA in infants born between 23 and 27 weeks GA.
To determine whether prophylactic ... Read More
Study will verify ability of infant Hydration Monitor (IHM) to assess changes of hydration
status in newborns and infants by means of ultrasound velocity measurements through muscle
tissues. Changes of tissue hydration will be followed during first days of life in newborns
and in acute diarrhea in small children during re-hydration therapy. Weighting and clinical
dehydration symptoms will be used as controls.
Breast milk is best food for neonates and preterm infants. However many handling would be
done if direct breastfeeding is not feasible, and it may result in nutrients change in human
milk. We investigate the influence of storage in different containers and different thawing
or heating methods on human milk nutrients.
The purpose of this study is to investigate the safety, efficacy and pharmacokinetics (PK)
of dexmedetomidine (DEX) at 3 different dose levels in infants, ages ≥28 weeks to ≤44 weeks
gestational age, administered as a loading dose followed by a continuous infusion for a
minimum of 6 hours and up to 24 hours in the neonatal intensive care unit (NICU), cardiac
intensive care unit (CICU), or pediatric intensive care unit (PICU).
It is well known that traffic accidents are one of the major reasons for death in childhood.
Unfortunately scientific and statistical data usually comes from developed countries. In
this study, the investigators will try to evaluate Turkish families' knowledge on Child
Passenger Safety, observe how they carry their babies in the car and investigated the
reasons behind the undesired behaviors.
To demonstrate a superior efficacy of BDP plus rescue salbutamol suspension for
nebulisation, compared to placebo plus rescue salbutamol, in the relief of symptoms of
asthma in young children with persistent symptoms of asthma.
Providing verbal counseling supplemented with both written and pictorial information then
verbal counseling alone is a more effective method of counseling parents with threatened
Neonates treated on Neonatal Intensive Care Units are often critically ill, subject to
numerous painful procedures and often dependent on mechanical ventilation. Mechanical
ventilation as well as painful conditions require a sufficient analgesia and or an
accurately regulated sedation. Newborns incapable of self-report are therefore dependent on
the assessment of the infants level of pain and sedation by the treating team.
The aim of this prospective, ... Read More
The aim of this study is to collect data on the early visual development of extreme
premature infants. The method is the measurement of flash visual evoked potentials and the
study population includes premature infants under the 28th weeks of gestation, who have
normal cranial ultrasound examinations, normal aEEG, no clinical neurological symptoms and
who have a normal ophthalmological status.
fVEP measurements were recorded from the first week of life ... Read More
Phototherapy is almost (beside exchange transfusion) the unique treatment for
hyperbilirubinemia of the newborn. Its efficacy to decrease bilirubin level (because the
light interacts with bilirubin at the skin level to transform it in water soluble products
eliminated in urine and stools without liver metabolism) relies on the irradiance dispensed
at the skin level by the device (in the 430-490nm range) and on the exposed surface of the
baby. In the past ... Read More
Antibiotic resistance is a major public health issue as multiresistant bacteria (MRB) are
increasing. Among the actions to control resistance, one is an interesting lead: to prevent
the emergence of resistant bacteria by limiting possibilities for bacteria to acquire
resistance. Mechanisms of resistance genes acquisition are deeply studied but there are few
data on the dynamic of acquisition over time. Among the genetic components that disseminate
resistance ... Read More
NIDCAP based developmental care is a method of looking after preterm infants that is guided
by the infant's behavioural cues, and that actively involves parents in the care of their
infant. There is limited evidence that outcomes for infants are improved if they receive
NIDCAP based care. This study evaluates the effects of introducing NIDCAP based care to a
level III neonatal intensive care unit, in the post - surfactant era, and also evaluates its
effects ... Read More
The purpose of this study is to study how people make decisions regarding delivery room
management for infants born extremely premature when survival and long term outcomes are
uncertain. The hypothesis is that the way in which information is presented will impact
There have been many advances in neonatal care in recent decades. However, the investigators
do not know if these children will grow up to be healthy or if they will have problems with
... Read More
The aim of the study is to compare the intubation conditions among propofol and remifentanil
versus midazolam and remifentanil in premature neonates with respiratory distress syndrome.
At the same time, to show the group of drugs that could let the neonates with no residual
sedation after the use of surfactant (the possibility of the premature neonates to be
readily extubated after the use of surfactant).
Vermont Oxford Network maintains a database for live born infants 401 to 1500 grams or 22 to
29 weeks gestational age who are born at participating hospitals or admitted to them within
28 days of birth, regardless of where the infant receives care.