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Clinical Trials: Pediatric Surgery

Source: Okayama University
Tranexamic acid(TXA) is an antifibrinolytic agent to reduce blood loss in cardiac surgery. Previous seven RCTs comparing effects of TXA in pediatric cardiac surgery showed conflict results. The reason why they showed mixed results would be the imbalance of patients population with regard to presence of cyanosis. TXA would reduce blood loss in pediatric cardiac surgery with well balanced patients population. Read More
Last Updated: 12 Oct 2009
Source: Octapharma
The purpose of this study is to investigate the safety, tolerability and efficacy of octaplas in pediatric patients who require replacement of multiple coagulation factors. Replacement of multiple coagulation factors in pediatric patients with acquired deficiencies due to liver disease and in pediatric patients requiring cardiac surgery or liver surgery. Read More
Last Updated: 01 Oct 2016
Source: Iladevi Cataract and IOL Research Center
The purpose of this study is to determine if intraocular infusion of low-molecular weight heparin (enoxaparin) influences postoperative inflammation following pediatric cataract surgery with intraocular lens (IOL) implantation. Read More
Last Updated: 27 Sep 2009
Source: Assiut University
The lung is at risk for ischemic insults during total cardiopulmonary bypass because lung perfusion is maintained solely by the bronchial arterial system Read More
Last Updated: 16 Jan 2017
Source: Iladevi Cataract and IOL Research Center
Cataract surgery is known to cause loss of corneal endothelial cells. In adults, it is reported that anywhere between 2 to 15% loss of corneal endothelial cell density occurs following cataract surgery. However, no data is available regarding endothelial changes after cataract surgery with IOL implantation in pediatric eyes. The aim of this study is to prospectively observe changes in endothelial cell density, coefficient of variation and hexagonality ... Read More
Last Updated: 02 Jan 2012
Source: Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle
Long surgical wait-times and limited hospital capacity are common obstacles to surgical care in many countries in sub-Saharan Africa (SSA). Ambulatory surgery might offer a solution to these problems. The aim is to study the introduction of ambulatory surgery in a pediatric hospital in SSA. This is a cross-sectional descriptive study which took place over 6 months. It includes all the patients assigned to ambulatory surgery in the Pediatric University ... Read More
Last Updated: 04 May 2016
Source: Baskent University
The purpose of this study is to compare two different cardioplegia solutions effect on postoperative Troponin-I and CK-MB levels after pediatric cardiac surgery. Read More
Last Updated: 05 Mar 2012
Source: Helsinn Healthcare SA
The objective of the study is to assess the safety and efficacy of two doses of IV palonosetron each administered as a single dose for the prevention of postoperative nausea and vomiting through 72 hours postoperatively in children aged 28 days up to 16 years inclusive undergoing surgical procedures requiring general endotracheal inhalation anesthesia. Read More
Last Updated: 16 Mar 2015
Source: Kuopio University Hospital
Acute appendicitis is the most common illness that brings pediatric patients to the hospital for surgical treatment. Abdominal pain is the symptom because of which the patients go to the hospital. Some patients have severe pain and need analgesics before the final diagnosis and before surgery. After surgery most patient experience pain and at least 80 % of the patients need postoperative pain medication. For two decades there has been a clinical guideline ... Read More
Last Updated: 18 Oct 2015
Source: Central Hospital, Nancy, France
Investigators compare the accuracy of the SpHb and hemocue with blood Hb levels Read More
Last Updated: 03 Aug 2016
Source: Assiut University
Directly following cardiac surgery for congenital heart disease; patients are not receiving routine turning every two hours to prevent pressure ulcers, because a negative influence on hemodynamic parameters is assumed. Investigators have suggested that lateral position may have clinically significant effects on oxygenation in cardiac surgery patients. Read More
Last Updated: 13 Jan 2017
Source: University of Foggia
The purpose of this study is to determine how Bispectral index (BIS) and Entropy EEG monitors agree between themselves and with end-tidal concentration of sevoflurane (ETsevo) in relationship with the age in the pediatric surgery setting. Bispectral index (BIS) and Entropy EEG monitors performance and utility is well established in adult general anesthesia. Their utility is yet undefined in the pediatric population as age seems to affect their ... Read More
Last Updated: 12 Sep 2016
Source: Oregon Health and Science University
The investigators primary objective is to determine if acute normovolemic hemodilution (ANH) for pediatric cardiac surgical patients decreases the volume of blood products transfused during surgery and the immediate post-operative period as compared to usual care. This study will enroll 24 pediatric heart surgery patients, aged 6 months to 3 years old undergoing either ANH prior to initiating cardiopulmonary bypass or the standard of care procedures for the ... Read More
Last Updated: 07 Jun 2016
Source: Advocate Health Care
The purpose of this study is to compare anti-inflammatory effects of two anti-fibrinolyntic drugs (Tranexamic acid versus Epsilon-aminocaproic acid) in pediatric patients undergoing pediatric cardiac surgery. Read More
Last Updated: 05 Aug 2016
Source: New York University School of Medicine
This study is trying to see if using precedex pre-operatively prevents emergence delirium in pediatric (ages 1-7) patients undergoing strabismus surgery. Read More
Last Updated: 07 Jun 2016
Source: Alcon Research
The purpose of this study is to describe the pharmacokinetics of AL-60371 otic suspension following two posologies of bilateral ototopical doses in pediatric subjects immediately after bilateral tympanostomy tube surgery. Read More
Last Updated: 03 Mar 2016
Source: Yonsei University
Effects of Choral Hydrate on Induction, Maintenance, and Recovery from Sevoflurane Anesthesia in Day-case Pediatric Surgery Read More
Last Updated: 08 Jun 2011
Source: Centre Chirurgical Marie Lannelongue
The purpose of this study is to determine tranexamic acid plasma levels in children undergoing cardiac surgery at risk of bleeding and to compare two dosing regimens. Read More
Last Updated: 20 Jul 2014
Source: Washington University School of Medicine
This study will determine the pharmacokinetics of intravenous (IV) methadone in children undergoing surgery. Read More
Last Updated: 12 Jan 2016
Source: Mansoura University
In this study, the investigators hypothesized that perioperative i.v. infusion of lidocaine in major abdominal pediatric surgery, may have a beneficial effect on hemodynamic and hormonal responses. Also, it could decrease the hospital stay, opioid requirement and hasten return of bowel function. Read More
Last Updated: 17 Apr 2012
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