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Clinical Trials: Palliative Medicine & Pain Management


Source: University of Michigan
To evaluate whether formal referral to The Symptom Management and Supportive Care Clinic improves symptom burden in advanced stage or recurrent gynecologic oncology chemotherapy patients compared with symptom management performed by the primary gynecologic oncologist. Read More
Last Updated: 24 May 2016
Source: Lille Catholic University
Pain is one of the major symptoms in palliative care units and often is very difficult to treat, being considered as a refractory pain. There are different causes of refractory pain: pain due to bed sores and ulcer bandages, carcinological or ischemic wounds or injuries, pain due to patients' reduced mobility, pain due to traumatological injuries, pain associated with a long-term bed confinement, etc. The investigators propose a prospective study to ... Read More
Last Updated: 01 May 2016
Source: Rigshospitalet, Denmark
Investigation of thermal thresholds and sensory mapping to thermal stimuli Read More
Last Updated: 27 Sep 2011
Source: National Institutes of Health Clinical Center (CC)
This study will investigate the most effective approach for managing pain and providing palliative care (lessening of pain or symptoms). Patients with advanced cancer who are enrolled in a National Cancer Institute (NCI) protocol and will undergo major surgery as part of their treatment may be eligible for this study. Participants will be randomly assigned to pain management provided by either 1) their attending physician or 2) the Clinical Center's Pain ... Read More
Last Updated: 02 Mar 2008
Source: University of Maryland
The purpose of this project is to test an innovative method for managing pain in acutely ill hospitalized patients who are not able to report their pain verbally to health care professionals. Nurses will use a Pain Assessment and Intervention for the Non-communicative (PAIN) Algorithm to guide assessment of pain, selection of pain medications, and management of medication side effects. The researchers will evaluate whether patients who are managed with the ... Read More
Last Updated: 29 Nov 2015
Source: Rigshospitalet, Denmark
This is an explorative study investigating potential nerve injury after VATS. Read More
Last Updated: 12 Jul 2010
Source: Duke University
The purpose of this study is to develop more effective ways to help patients and their caregivers cope with cancer pain. The investigators are looking at the usefulness of a Caregiver-Guided Pain Management Training Intervention versus Pain Education. Read More
Last Updated: 03 Nov 2016
Source: University of Washington
Patients in isolated rural settings often lack easy access to pain care and specialist services. Yet rural residents are more likely than their urban counterparts to be older; be in poorer overall health; suffer from more chronic or serious illnesses and disabilities; be uninsured or underinsured; and live in poverty. Telehealth is an emerging method of health care delivery that has been found useful and effective in many clinical settings and specialties. ... Read More
Last Updated: 23 Feb 2014
Source: Assistance Publique Hopitaux De Marseille
80% of palliative care cancer patients suffer from severe pain. The management of these pain improves the quality of life of these patients. The management of opioid pain refractory to date remains a difficulty for caregivers. Hypophysectomy performed to try to control hormone-dependent neoplasia also help relieve pain associated with lesions secondary cancer. The surgical hypophysialis radio Gamma Knife ® was recently performed on a small number of ... Read More
Last Updated: 17 Dec 2015
Source: Norwegian University of Science and Technology
The rising incidence of cancer and the rapidly increasing number of people living longer with incurable disease, accentuates the need for optimal symptom management throughout the disease trajectory. Thanks to the medical and technological development, and the increased interest in palliative care research, palliative medicine has gradually become more evidence based. Patients with advanced cancer experience multiple symptoms at the time with fluctuating ... Read More
Last Updated: 31 Jul 2016
Source: Angelini Farmacéutica
Patients treated in Palliative Care Units are potentially fragile patients, especially in our case, which are cancer patients. The management of these patients is usually done from experience, because these patients rarely meet criteria for clinical trials, as their inclusion could affect results obtained in the trial. There is insufficient clinical information on the quality of life of cancer patients with breakthrough pain treated in palliative care units ... Read More
Last Updated: 18 Jul 2016
Source: VA Office of Research and Development
Improving end-of-life care is of critical importance to the VA as it faces an increasingly aging and dying veteran population. Previous work within and outside of the VA has demonstrated serious deficiencies in the quality of care delivered near the end of life. Moreover, veterans in the VA system suffer from a higher rate of chronic and life-limiting illnesses and decrements in health-related quality of life compared with the age-matched controls. In FY2000 ... Read More
Last Updated: 05 Apr 2015
Source: Teva Pharmaceutical Industries
The purpose of this study is to evaluate the safety and tolerability of OraVescent fentanyl when used long-term to relieve breakthrough pain in opioid tolerant cancer patients. Read More
Last Updated: 07 May 2014
Source: Albert Einstein College of Medicine of Yeshiva University
This randomized clinical trial studies a palliative care program in improving the quality of life of patients with high-risk gynecologic malignancies that is original or first tumor in the body (primary) or has come back (recurrent). Palliative care is care given to patients and their families facing the problems associated with life-threatening illness, through the prevention and relief of suffering by means of early identification and impeccable assessment ... Read More
Last Updated: 14 Oct 2015
Source: University of British Columbia
The purpose of this within-subjects randomized controlled trial is to determine whether two music therapy interventions are efficacious in reducing pain symptoms, in order to improve the quality of care for children in pediatric hospice. The investigators hypothesize that both music therapy interventions, live guitar and vocal intervention and vibroacoustic intervention, will reduce behavioural pain scores and that behavioural pain scores will correlate with ... Read More
Last Updated: 21 Apr 2015
Source: Celgene
This is a multicenter, open-label study in adult subjects with Type 1 Complex Regional Pain Syndrome. Subjects diagnosed with unilateral Type 1 CRPS will be enrolled sequentially to receive CC-5013 10 mg/day orally. For each subject the study consists of two phases: Pre-treatment phase(1 wk) and treatment phase (12 wks) Read More
Last Updated: 27 Dec 2007
Source: NIH AIDS Clinical Trials Information Service
To determine the safety and efficacy of SNX-111 in controlling severe, chronic pain in cancer and AIDS patients. Read More
Last Updated: 22 Jun 2005
Source: GW Pharmaceuticals Ltd.
The purpose of this study is to determine whether Sativex® and GW-2000-02 are effective in the management of subjects with intractable cancer-related pain. Read More
Last Updated: 12 Jun 2013
Source: AcelRx Pharmaceuticals, Inc.
The purpose of this research study was to evaluate ARX-F02 (Sufentanil NanoTab) versus placebo ("sugar" pill or inactive substance) in the management of breakthrough pain in cancer patients. Read More
Last Updated: 17 Dec 2014
Source: University Hospital, Limoges
Number of patients in mobile palliative care units have pain of both nociceptive and neuropathic origin. In certain cases, procedures of locoregional analgesia can be helpful. The Purpose of this study is to evaluate the impact of techniques of locoregional analgesia in a palliative population Read More
Last Updated: 30 Aug 2015
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