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Clinical Trials: Otolaryngology


Source: Ethicon, Inc.
Evaluating clinical performance of Hemostatic Matrix with bovine thrombin in achieving hemostasis in patients undergoing endoscopic sinus surgery. Read More
Last Updated: 10 Jul 2006
Source: Khon Kaen University
The purpose of this study is to determine the outcome of cochlear implant including post operative hearing ability, developing of language, complication from cochlear implant, quality of life, and success factor of cochlear implant. Read More
Last Updated: 08 Jul 2016
Source: Duke University
The goals of this project are aimed at the following: 1. Identifying psychiatric comorbidity in patients presenting to the HNSCS clinic 1F and Duke Otolaryngology of Raleigh clinic using the validated assessment tool Brief Symptom Inventory (BSI-18) and the patient control scale. The BSI-18 is an 18 question and patient control an 8 item tool that takes about four minutes to complete. 2. Gathering data regarding patient satisfaction in ... Read More
Last Updated: 05 Oct 2016
Source: Otonomy, Inc.
The purpose of this study is to evaluate the safety of OTO-104 in subjects with unilateral Meniere's disease. The effectiveness of OTO-104 to reduce the symptoms of Meniere's disease will also be evaluated. Read More
Last Updated: 06 Jun 2011
Source: Intersect ENT
The purpose of the study is to determine whether a steroid-eluting sinus implant is effective in improving chronic sinusitis symptoms in patients who experience recurrent blockage of the sinuses by polyps sometime after sinus surgery. Read More
Last Updated: 17 Jan 2016
Source: Washington University School of Medicine
The study will involve adult otolaryngology patients over the age of 18 years undergoing open or endoscopic/robotic tumor resection involving the mucosal surfaces of the oral cavity, oropharynx, hypopharynx and larynx at Washington University Medical Center. Eligible patients will be recruited from the otolaryngology head and neck cancer clinic during preoperative visits. Participants will be randomized to active or placebo drug and will receive study drug ... Read More
Last Updated: 03 Oct 2016
Source: University of Alabama at Birmingham
The purpose of this project is to determine if pre-treatment swallowing exercises can improve post-treatment swallowing function in patients undergoing radiation with or without chemotherapy for advanced squamous cell carcinoma of the head and neck. Read More
Last Updated: 11 Mar 2015
Source: Entellus Medical, Inc.
A prospective, post-approval registry study assessing subject rhinosinusitis symptomatic status over time following treatment with FinESS Sinus Treatment using self-administered quality of life survey data. Read More
Last Updated: 26 Jun 2011
Source: Washington University School of Medicine
Patient satisfaction is an important metric currently used to rate quality of healthcare in hospitals. Maximizing patient satisfaction scores is therefore significantly beneficial to any hospital establishment. Recent studies have shown patient satisfaction depends on multiple factors, including patient involvement in treatment decision-making processes and patients' knowledge of treatment options. Internal review of departmental patient satisfaction survey ... Read More
Last Updated: 21 Sep 2016
Source: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
The purpose of this project is to develop an accurate method to identify patients that suffer from acid reflux, but may not present with classic reflux symptoms (such as heart burn). Additionally, it is the purpose of this project to utilize the Unsedated Small-caliber Endoscopy (USE) to assess the prevalence of Barrett's esophagus in a population of patients with laryngopharyngeal reflux (LPR) symptoms and to define normal patterns of LPR. Laryngopharyngeal ... Read More
Last Updated: 01 May 2011
Source: Chiang Mai University
Unilateral posterior canal benign paroxysmal positional vertigo (BPPV) cases will be randomized to treat with single or multiple cycles of canalith repositioning procedure.The treatment outcomes will be assessed at 7th and 28th days. Read More
Last Updated: 06 Jan 2017
Source: Advanced Bionics
The purpose of this study is to determine the feasibility of preserving low-frequency acoustic hearing in adults with a moderate degree of hearing loss in the low frequencies and severe-to-profound hearing loss in the mid-to-high frequencies who are implanted with the HiRes™ 90K Advantage implant with HiFocus™ Mid-Scala electrode. Read More
Last Updated: 19 May 2015
Source: Merz Pharmaceuticals GmbH
The purpose of this study is to investigate the safety and efficacy of neramexane mesylate in the treatment of subjective tinnitus in comparison to placebo. Read More
Last Updated: 26 Nov 2012
Source: Merz Pharmaceuticals GmbH
The purpose of this study is to investigate the long-term safety and tolerability and efficacy of neramexane mesylate in the long-term treatment of subjective tinnitus after a completed double-blind randomized placebo controlled study Read More
Last Updated: 26 Nov 2012
Source: Office of Rare Diseases (ORD)
OBJECTIVES: I. Define the growth rates and clinical course of NF2-related tumors in patients with neurofibromatosis type 2. Associate growth rate with physical function. Read More
Last Updated: 26 Sep 2005
Source: Temple University
This study will be a prospective, randomized, unblinded but controlled trial. Patients presenting to the Otolaryngology clinic who are diagnosed with laryngopharyngeal reflux disorder related dysphonia and meet inclusion criteria will be eligible to enroll in the study. Subjects will be randomized to one of three treatment arms, voice therapy, anti-reflux therapy, or a combination of voice therapy and anti-reflux therapy. Reflux symptom index (RSI) scores, ... Read More
Last Updated: 06 Jul 2016
Source: Carbylan Therapeutics, Inc.
The purpose of this study is to evaluate the safety and effectiveness of AdvaCoat® sinus gel, a nasal/sinus dressing, for adhesion prevention following endoscopic ethmoid sinus surgery. Subjects were randomized to receive AdvaCoat applied to the right or left middle meatus tissues and Merogel applied to the middle meatus tissues on the opposite side. Read More
Last Updated: 21 Apr 2009
Source: Naryx Pharma
The primary objective of the study is to evaluate the safety and efficacy of SPRC-AB01 versus placebo for treatment of chronic sinusitis in subjects who have had sinus surgery. Read More
Last Updated: 12 Mar 2008
Source: Otonomy, Inc.
The purpose of this study is to evaluate the effectiveness of OTO-104 for the treatment of Meniere's disease. Read More
Last Updated: 17 Aug 2015
Source: Chang Gung Memorial Hospital
New designs of 6-year undergraduate medical education (UME) in Taiwan mainly include (1) integral curricula of body organ system, (2) multiple methods of clinical teaching and assessment, and (3) generalism in UME. Accompany with decreasing educational hours in the classrooms and hospital, essential but minor components of primary healthcare such as ophthalmology and otolaryngology-head and neck surgery (ORL-HNS) is disproportionately under-represented in ... Read More
Last Updated: 19 Nov 2016
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