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Clinical Trials: Oral & Maxillofacial Surgery

Source: Shenzhen SiBiono GeneTech Co.,Ltd
This is multicenter, open-label, randomized, active-controled, phase IV study of local direct intra-tumor injection of rAd-p53 monotherapy, with concurrent chemotherapy , or combination with surgery for treatment of advanced oral and maxillofacial malignant tumors. Read More
Last Updated: 05 Apr 2012
Source: Shanghai 9th People's Hospital
The purpose of this study is to determine whether dexmedetomidine is effective in the treatment of emergence delirium of preschool children undergoing oral maxillofacial surgery. Read More
Last Updated: 01 Aug 2011
Source: Atlantic Center for Oral and Maxillofacial Surgery
The purpose of this study is to determine if the use of propofol only to achieve procedural sedation for the removal of third molars is both safe and effective. Read More
Last Updated: 20 Oct 2010
Source: University of Cologne
Patients undergoing major procedures in oral and maxillofacial surgery more often develop a systemic inflammatory response syndrome (SIRS) in the first days of postoperative critical care therapy than patients with a comparable major surgery in other regions. The reasons for this finding are unknown and have not been studied in depth so far. We hypothesize that surgical trauma in this region might activate pro-inflammatory pathways. By examining the proteome ... Read More
Last Updated: 06 Dec 2014
Source: Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Implant placement may trigger bone trauma, which might result in 3-dimensional bone changes. While the process of peri-implant disease is not well understood, implant position within the bony structure might play a role. However, there is no data available on this regard. Read More
Last Updated: 17 Oct 2016
Source: Shanghai 9th People's Hospital
The purpose of this study is to compare the sedation effect of dexmedetomidine and target controlled remifentanil for awake nasotracheal fibreoptic intubation in patients undergoing oral maxillofacial surgery. Read More
Last Updated: 21 Oct 2012
Source: Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Overcoming the vertical and horizontal bone deficiency in the posterior maxillae are considered as the most challenging scenarios for implant-supported oral rehabilitation in modern implant dentistry. Therefore, a comprehensive and precise understanding of such anatomical structures are needed to avoid potential complications that ultimately might jeopardize the treatment outcome. Cone-beam computerized tomography (CBCT) offers some advantages to ... Read More
Last Updated: 12 Jul 2016
Source: Universidade Federal do Rio Grande do Norte
The study set out to evaluate the efficacy of two antibiotic prophylaxis regimens in patients with facial fractures admitted to the Oral and Maxillofacial Surgery and Traumatology services of the Onofre Lopes University Hospital attached to the Federal University of Rio Grande do Norte. Read More
Last Updated: 17 Nov 2013
Source: NextGen Company Limited
The purpose of this study is to evaluate safety and efficacy of gene-activated matrix ("Nucleostim") for regeneration of bone tissue in maxillofacial area. Patients with congenital and acquired maxillofacial defects (sockets of extracted teeth, bone defects after injuries, surgeries, excision of benign neoplasms and pseudotumors, etc.) or alveolar bone atrophy will be included into the study. Read More
Last Updated: 20 Mar 2016
Source: Federal University of Minas Gerais
The purpose of the present study was to compare some hematologic parameters and operation time in patients who underwent esthetic bimaxillary surgery under hypotensive anesthesia. Read More
Last Updated: 09 Feb 2015
Source: AZ Sint-Jan AV
Background Bone augmentation provides a solution for patients with a severely atrophic jaw to achieve immediate fixed prosthetic rehabilitation. Studies reporting total bone volume changes are lacking. Objectives The investigators aim to determine the level of total bone volume remodeling at 6, 24 and 36 months post-surgery in patients who underwent immediate prosthetic rehabilitation through a cranial bone-grafted maxilla in combination with ... Read More
Last Updated: 20 Jun 2016
Source: Universitaire Ziekenhuizen Leuven
The aim of this study is to get a clear view on current practice of surgical third molar removal in Belgium and the association with morbidity and complications. For this prospective cohort study, patients who visit the outpatient department of Oral and Maxillofacial Surgery of the University Hospitals Leuven or hospitals affiliated with the Flemish Hospital Network will be participating. All included patients are referred from primary dental providers for ... Read More
Last Updated: 24 Oct 2016
Source: University of Sao Paulo
To evaluate the effectiveness in the use of an educational material through: Assessment of knowledge about post-operative orthognathic surgery; assessing levels of anxiety with the survey of Anxiety Inventory-STATE-TRAIT; clinical evaluation of self-care in the management of postoperative signs and symptoms Read More
Last Updated: 03 Dec 2014
Source: Norwegian University of Science and Technology
The purpose of this clinical investigation is to evaluate acute and longlasting side effects in patients undergoing radiotherapy for cancer treatment in the head and neck area. Read More
Last Updated: 11 Aug 2014
Source: Beijing Stomatology Hospital
The aim of the study is to construct a register system of oral and maxillofacial malignant tumors based on a prospective, observational, real-world study in north Chinese population. Read More
Last Updated: 29 Nov 2016
Source: VA Office of Research and Development
This study proposes to develop a computer-based software tool that will allow surgeons to plan and simulate surgery for patients with jaw trauma. Read More
Last Updated: 11 Dec 2014
Source: CEL-SCI Corporation
The purpose of this study is to determine whether LI administered in combination with cyclophosphamide, indomethacin and zinc (CIZ) in a multivitamin combination prior to standard of care therapy (surgery followed by radiotherapy or concurrent radiochemotherapy) is safe and will increase the overall survival of subjects with previously untreated squamous cell carcinoma of the oral cavity or soft palate at a median of 3 years Read More
Last Updated: 10 Aug 2016
Source: Central South University
Difficult airways is still a challenging issue for the anesthesiologists in spite of the development of various techniques.Shikani optical stylet(SOS), combining the features of fiberoptic bronchoscope and a lightwand, has been used for orotracheal intubation with difficult airways. As compared with fiberoptic bronchoscope, SOS is less expensive, easy to learn and more durable. However, it remains elusive whether SOS can be used in the nasotracheal ... Read More
Last Updated: 30 Apr 2012
Source: BonusBio Group Ltd
The purpose of this clinical study is to evaluate the safety and the efficacy of BonoFill-II as a bone filler containing the patient's own (autologous) adipose (fat) tissue-derived cells in reconstructing bone in two clinical indications: 1. Bone augmentation (e.g. sinus augmentation) 2. Bone grafting after removal of cysts from jaws Read More
Last Updated: 02 Jan 2017
Source: University of Pennsylvania
Bisphosphonates are drugs that prevent bone loss by blocking the activity of cells that normally resorb bone. The most common examples of these drugs are Boniva and Fosamax. These drugs are available for oral or intravenous dosing and are prescribed at daily, weekly, biweekly, or monthly intervals. Among the many thousands of individuals who currently take these medications, certain individuals experience "atypical" femur fractures preceded by prodromal ... Read More
Last Updated: 02 May 2016
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