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Clinical Trials: Ophthalmology

Source: Association for Innovation and Biomedical Research on Light and Image
To review the safety and efficacy of injections with Ozurdex (700 μg dexamethasone) in clinical practice management of patients with DME. Read More
Last Updated: 18 Jan 2016
Source: Erasmus Medical Center
Infantile esotropia is corrected in most cases by bilateral recession of the medial rectus muscles (BR) or by unilateral recession of the medial rectus muscle and resection of the lateral rectus muscle (RR). We compared the outcome of these techniques in a randomized prospective study. Read More
Last Updated: 16 Mar 2006
Source: Ophthalmology Consultants, Ltd.
The purpose of this study is to demonstrate that Besivance is equal to Vigamox in safety and tolerance when used prophylactically in subjects undergoing routine cataract surgery. Read More
Last Updated: 17 Oct 2011
Source: Jaeb Center for Health Research
The purpose of this study is to assess whether glycemic control (assessed with HbA1c measurement) in individuals with type 1 or type 2 diabetes can be improved with a point-of-care measurement of HbA1c in the ophthalmologist's office combined with a personalized risk assessment for diabetic retinopathy and other complications of diabetes. Read More
Last Updated: 24 Aug 2016
Source: University Hospital Tuebingen
Tuebingen High Altitude Ophthalmology Study to investigate the effects of high altitude on retinal structure and function as well as anterior chamber in regard to acute mountain sickness. Read More
Last Updated: 01 Dec 2010
Source: Allergan
The objectives of this study are twofold •To evaluate the safety and efficacy of 0.1% AGN-195263 administered twice daily compared to its vehicle in patients with evaporative dry eye (EDE) •To evaluate the systemic pharmacokinetics of 0.1% AGN-195263 administered twice daily in patients with EDE Read More
Last Updated: 14 Dec 2016
Source: Peking University
To undertake a prospective randomized clinical study for treating retinal detachment due to myopic macular holes, utilizing pneumatic retinopexy versus pars plana vitrectomy with gas tamponade.To determine the efficiency of pneumatic retinopexy with C3F8 in the treatment of retinal detachment due to myopic macular hole. Read More
Last Updated: 10 Jun 2007
Source: University Hospital, Bonn
The Ranibizumab in Pigment Epithelium Tears Secondary To Age-Related Macular Degeneration (RIP) Study is a prospective, multicenter, uncontrolled, interventional phase 2 clinical trial that investigates the effect of fixed monthly intravitreal injections of ranibizumab (Lucentis, Novartis Pharma, Germany) on visual acuity and retinal morphology over a study period of 12 months in 30 patients. Read More
Last Updated: 11 May 2016
Source: University of Milan
This is a data revision with a focus on 24 hour perfusion pressures of data from a previous randomized, double masked, multicenter clinical trial. The aim was to compare the effect of bimatoprost and the fixed combination of latanoprost and timolol (LTFC) on 24-hour mean intraocular pressure (IOP) after patients are switched from a nonfixed combination of latanoprost and timolol. The main findings of the original trial had been published on Ophthalmology ... Read More
Last Updated: 28 May 2014
Source: River Vision Development Corporation
The purpose of this study is to evaluate the safety, tolerability and effectiveness of a fully human antibody compared to placebo in the treatment of patients with active thyroid eye disease. "Funding Source - FDA OOPD" Read More
Last Updated: 22 Nov 2016
Source: Quark Pharmaceuticals
This is an open-label, dose escalation, safety, tolerability and pharmacokinetic study, where active study drug (QPI-1007) will be given to all patients who participate. This study will determine whether QPI-1007 is safe when it is injected into the eye. The study will also reveal if there are any side effects of the drug and how long it takes for the body to clear the drug. Read More
Last Updated: 08 May 2013
Source: Turkish Ophthalmology Society
Objectives: Behçet's disease (BD) is a systemic vasculitis. Since vascular endothelial dysfunction plays a prominent role in the pathogenesis of the disease, we considered angiogenic cytokines as an interesting target for investigation in BD. The aim of this study was to investigate the possible role of angiogenin, vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in the pathogenesis of BD. Design and Methods: Sixty five ... Read More
Last Updated: 30 Oct 2012
Source: California Pacific Medical Center Research Institute
The overarching purpose of this project is to provide diabetes education to the diverse patient population at the Lions Eye Clinic, a resident-run ophthalmology practice at California Pacific Medical Center. Because of high clinic volume in a teaching environment, our patients often experience long wait times. The goal of this program is to utilize this wait time for diabetes education, a much-needed corollary to the eye care that patients receive at our ... Read More
Last Updated: 24 Jul 2016
Source: University of Pennsylvania
The purpose of the study is to evaluate the relative efficacy and safety of treatment of neovascular AMD with Lucentis on a fixed schedule, Avastin on a fixed schedule, Lucentis on a variable schedule, and Avastin on a variable schedule. A five year follow-up visit is being conducted in 2014 to gather information on long term outcomes. Read More
Last Updated: 09 Oct 2016
Source: Orasis Pharmaceuticals Ltd.
A study to Establish Safety, Tolerability, and Efficacy of PresbiDrops in Presbyopic Subjects. Read More
Last Updated: 15 Nov 2016
Source: The Eye Center and The Eye Foundation for Research in Ophthalmology
Evaluation of the safety and efficacy of surface ablation followed by Collagen Cross-linking in patients with keratoconus Read More
Last Updated: 09 Jul 2014
Source: Queen's University
The hypothesis is that pediatric patients with increased levels of anxiety on the day of surgery, in particular at point of anesthetic induction, will demonstrate decreased compliance with assessment in ophthalmology clinic postoperatively. Read More
Last Updated: 03 Mar 2016
Source: MD Stem Cells
This study will evaluate the use of autologous bone marrow derived stem cells (BMSC) for the treatment of retinal and optic nerve damage or disease. Read More
Last Updated: 02 Jan 2017
Source: Lux Biosciences, Inc.
The objective of this study is to evaluate the safety and efficacy of LX211 as therapy in subjects with active non-infectious uveitis Read More
Last Updated: 08 Oct 2012
Source: Lux Biosciences, Inc.
The objective of this study is to evaluate the safety and efficacy of LX211 as therapy in subjects with clinically quiescent non-infectious uveitis Read More
Last Updated: 20 Jun 2012
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