Pegylated Liposomal Doxorubicin as well as Carboplatin have been showed efficacy in
monotherapy as in combination therapy of gynaecologic tumours. As there is no common
standard in the therapy of recurrent ovarian carcinoma, tumours of the uterus nor for
non-epithelial ovarian tumours at time of designing of this study, this trial shall evaluate
the new and well tolerated combination therapy consisting of Pegylated Liposomal Doxorubicin
This trial will assess the efficacy and safety of PGL4001 with concomitant iron
administration versus placebo with concomitant iron administration, over a 3-month period
for the pre-operative treatment of pre-menopausal women suffering from excessive uterine
bleeding due to uterine myoma.
The purpose of this study is to determine if a multimodal immunization program carried out
in obstetrics and gynecology (ob/gyn) practices would be more effective in improving ob/gyn
patients' immunization rates, specifically for Tdap, HPV, and influenza vaccines, than the
usual care provided to patients in ob/gyn practices.
It is the purpose of this study to evaluate the relationship between a low transverse,
vertical midline, and supra-panicular high transverse skin incisions and the rate of wound
complications in women with a BMI of 40 or greater undergoing a cesarean section for
delivery. So far, the choice of incision for the morbidly obese is based only on case
reports. No randomized controlled trials have been done up to date comparing these methods.
It is our hope that a ... Read More
The purpose of this study is to collect and assess information on safety and efficacy of
fondaparinux in patients undergoing abdominal surgery in urology, obstetrics and gynecology
departments who are at high risk of venous thromboembolism.
The use of virtual reality simulation training in obstetrics and gynecology has not been
widely studied. The investigators hypothesized that residents randomized to the trainer
would not perform differently when compared with those who are not randomized. Residents in
Obstetrics and gynecology are randomized to a 4 month training course on our simulator. They
are objectively evaluated performing various laparoscopy tasks prior to and after the
The purpose of the study is to investigate the effect of four different follow-up strategies
on postoperative recovery following vaginal or abdominal hysterectomy for benign conditions.
Furthermore the investigators aim to examine associations between preoperative thresholds
for pain (thermal and pressure) and postoperative pain and development of chronic pelvic
pain after benign hysterectomy.
This is a 3-arm, randomized, double-blind, double-dummy, and controlled clinical study over
6 months of treatment to evaluate the metabolic and clinical efficacy as well as the safety
of DLBS3233 alone, metformin and combination of both, in improving metabolic and
The purpose of this study is to determine whether the Ice-Sense, a novel cryotherapy system
(a system that freezes tissues), is safe and effective in the treatment of benign breast
tumors such as fibroadenoma.
Obstetrics and gynecology residents are deemed to be proficient in transvaginal ultrasound
(TVUS) upon graduation from an accredited program, although TVUS education in residency is
not standardized. The objective of this study is to assess for improvement in transvaginal
ultrasound knowledge among residents after viewing an educational DVD.
As part of the continuing effort to study the benefit and risks of 17P and preterm delivery,
this study is designed as a multi-center, randomized, double-blind, vehicle-controlled
clinical trial of 17P for the prevention of preterm birth prior to 35 weeks, 0 days of
gestation in women with a singleton pregnancy, aged 18 years or older, with a previous
singleton spontaneous preterm delivery. The study also includes a population pharmacokinetic
(PK) substudy ... Read More
Fetal Growth Restriction (FGR) remains a challenging topic for clinicians, researchers and
policy makers, and a central question is how to improve the performance of screening during
pregnancy in order to provide appropriate care. The recent recommendations and reporting of
French results have raised awareness of the need to improve growth screening in France.
Based on the existing literature, the hypothesis is that a greater investment in growth
monitoring ... Read More
This is a clinical registry of an FDA approved device system called the Genesys Hydro
ThermAblatorTM (HTA) system (Boston Scientific). The HTA system's intended use is to be
inserted, by a trained physician, into the uterus, where it will fill and circulate fluid
that is warm enough to change the characteristics of the uterine lining. This is done with
the anticipated result of improving menstrual bleeding symptoms.
The purpose of this FDA-mandated registry ... Read More
Head to Head comparison of perioperative complications and secondary the impact of operation
techniques with or without mesh on patients suffering from pelvic organ prolapse on quality
Intrauterine balloon tamponade in the management of postpartum hemorrhage in the obstetrics
emergency ward in menoufiya university hospitals as a low resource setting.Guidelines for
the management of postpartum hemorrhage involve a stepwise approach including the exclusion
of retained products and genital tract trauma. Uterine atony, which is the most common
cause, is dealt with uterine rubbing and various uterotonic agents. Among the new modalities
... Read More