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Clinical Trials: Microbiology & Virology

Source: University of Pittsburgh
The study will identify patients with infections commonly observed in transplant recipients, describe the epidemiology of their infection, study the risk factors associated with various infections and examine strategies of early diagnosis and prevention of infection Read More
Last Updated: 15 Dec 2015
Source: National Institute of Allergy and Infectious Diseases (NIAID)
A Phase IV, randomized, multicenter trial to assess the immunogenicity and safety of BioThrax® in varying dose regimens with the primary objective of obtaining information on possible dose-sparing strategies in the event of a major biothreat. Read More
Last Updated: 23 Apr 2014
Source: National Institute of Allergy and Infectious Diseases (NIAID)
Approximately 216, and up to 240, healthy males and non-pregnant females, 18 to 49 years old, inclusive, will be enrolled over a 5-month period into this multicenter, randomized, double-blinded, controlled Phase I study. Subjects who meet the entry criteria for the study and provide informed consent will be randomized 2:1 between adjuvanted and unadjuvanted vaccine and placed into one of 6 groups (see table) to receive two doses of an intramuscular subvirion ... Read More
Last Updated: 16 Jan 2013
Source: National Institute of Allergy and Infectious Diseases (NIAID)
Due to recent concern of biowarfare and bioterrorism, the US government is making efforts to improve its ability to protect citizens against the smallpox virus. This study will evaluate safety of IMVAMUNE®, an investigational smallpox vaccine, and its ability to stimulate the immune system (the body's defense system). Two vaccine preparations have the same name but one is a liquid and one is a powder that has liquid added just before it is given. The vaccine ... Read More
Last Updated: 03 Dec 2014
Source: National Institute of Allergy and Infectious Diseases (NIAID)
This Phase II randomized, double-blinded, controlled study in up to 1000 males and non-pregnant females, 19 to 64 years old, inclusive, who are in good health and meet all eligibility criteria is designed to provide data on an A/H7N9 vaccine made with HA antigen derived from the influenza A/Shanghai/2/2013 virus. Read More
Last Updated: 02 Mar 2016
Source: Oulu University Hospital
The purpose of this study is to find out if we can predict the progress of acute upper respiratory tract infection to acute bacterial rhinosinusitis in Finnish conscripts by symptoms, clinical, endoscopic or radiological findings, middle meatal swab samples or nitric oxide measurement. Read More
Last Updated: 28 Oct 2013
Source: C3 Jian, LLC
Part A: Open-label, multiple arm, safety, microbiology and pharmacokinetic (PK) study in healthy adult male and female subjects 18-75 years of age. All subjects will be assessed for safety and microbiology parameters. A subset of subjects will be assessed for pharmacokinetic parameters. No longer enrolling study subjects in Part A. Part B: Open-label, multiple arm, safety and microbiology study in healthy adult male and female subjects 18-75 years of age. ... Read More
Last Updated: 15 Dec 2016
Source: Crucell Holland BV
After prophylactic vaccination with CR8020, a monoclonal antibody, subjects will be challenged with the H3N2 virus. The protective efficacy, safety, tolerability, pharmacokinetics, and potential immunogenicity will be assessed. Read More
Last Updated: 02 Mar 2014
Source: C3 Jian, LLC
The purpose of this single-blind study is to evaluate whether C16G2 Varnish administered in multiple doses can effectively kill the bacteria in the oral cavity that cause dental caries. Read More
Last Updated: 21 Dec 2016
Source: Aarhus University Hospital
Prospective, observational study of the microbiology of patients referred to a tertiary care center with severe acute tonsillitis, peritonsillar cellulitis, or infectious mononucleosis. Read More
Last Updated: 20 Mar 2016
Source: Vertex Pharmaceuticals Incorporated
Observational follow-up study to assess long-term response to telaprevir and to evaluate changes in Hepatitis C virus over time. Read More
Last Updated: 25 Feb 2014
Source: University of Pittsburgh
This research is important because it allows for the determination of resistance rates to antibiotics that may not be frequently tested by the clinical microbiology laboratory at University of Pittsburgh Medical Center (UPMC)-Presbyterian. It also will provide antibiotic minimum inhibitory concentrations (MICs) for these pathogens which may help in identifying the best empiric antibiotic option for gram-negative blood stream infections based on known ... Read More
Last Updated: 15 Dec 2015
Source: Centre Hospitalier Universitaire de Saint Etienne
Epidemics and infectious diseases in general, punctuate much of the activity of an emergency service. The impact of winter infections is particularly important to vulnerable populations such as infant during bronchiolitis epidemics and the elderly during seasonal influenza. Each year, these epidemic phenomena lead to disorganization of emergency services and healthcare teams by lack of anticipation and organizational measures in particular to manage the ... Read More
Last Updated: 02 Aug 2016
Source: C3 Jian, LLC
The purpose of the clinical study is to evaluate the safety and bacterial impact of study drug (C16G2) administered in multiple oral gel doses to adolescent and adult dental subjects. Read More
Last Updated: 21 Aug 2016
Source: Memorial University of Newfoundland
Asymptomatic bacteriuria (AB) is a condition in which bacteria are detected in urine culture without urinary symptoms. The inappropriate use of antibiotic treatment for AB selects bacterial flora to express resistance mutations. Reducing inappropriate antibiotic use for AB is difficult, since the microbiology laboratory cannot distinguish patients with AB. The investigators study will use a restricted laboratory report requesting the physician to call the ... Read More
Last Updated: 09 Jun 2016
Source: Pfizer
The aim of this study is to specify the serotype distribution of Streptococcus pneumoniae that causes invasive diseases at children and adults in Turkey. Read More
Last Updated: 05 Dec 2016
Source: Public Health England
The study involves the measurement of immune response to vaccination with three doses of a meningococcal B vaccine and a single dose of a meningococcal ACYW conjugate vaccine in healthy adults (Laboratory workers). The study will be completed at the Manchester Medical Microbiology Partnership in the UK and will enrol staff who may be at potential occupational exposure to meningococci. Blood samples will be taken before and after each vaccination and used to ... Read More
Last Updated: 26 Mar 2012
Source: Mahidol University
The purpose of this study is to determine amoxicillin is effective in the prevention of wound infection in normal labor. Read More
Last Updated: 30 Nov 2015
Source: Institute of Virology, Vaccines and Sera, Torlak
A Phase 3, double-blind, randomized, placebo-controlled trial of a seasonal, trivalent, split, inactivated influenza vaccine produced by Torlak. Read More
Last Updated: 11 Dec 2016
Source: C3 Jian, LLC
The focus of the study is to evaluate the safety of multiple study drug administrations and the study drug selectively reducing or eliminating a specific bacteria in the mouth. It will compare a liquid and gel product applied in different modes. Read More
Last Updated: 26 Jul 2016
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