Obese HIV-positive women with Metabolic Syndrome (HIV-MS) and obese HIV-negative women with
Metabolic Syndrome will be studied before and after achieving moderate (6%-8%) diet-induced
weight loss. The investigators hypothesize that health markers will improve in both groups
but that the improvement will be blunted in the women with HIV-MS.
Source: Heilongjiang University of Chinese Medicine
Berberine has showed effective in lowering blood sugar levels in db/db mice and
anti-dyslipidemia in human.Studies on the effect of berberine on metabolic and hormonal
features of women with polycystic ovary syndrome (PCOS) are lacking.The objective of this
study is to examine the effect of Berberine metabolic and hormonal parameters and insulin
resistance in obese patients with PCOS.
Respiratory failure is a common consequence of chronic obstructive pulmonary disease (COPD).
A concurrent metabolic alkalosis may worsen the respiratory failure, as a higher pH in blood
(and thus in cerebrospinal fluid) results in a weaker respiratory drive. Use of diuretics is
the most common cause of metabolic alkalosis.
When a patient with an acute exacerbation of a respiratory failure is also alkalotic, there
are (at least theoretical) reasons to lower ... Read More
This project aims to identify whether therapeutic substitution of aripiprazole for
risperidone or olanzapine, combined with standard nutrition intervention, will impact the
metabolic changes associated with antipsychotic treatment in children and adolescents.
Source: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
The incidence of nephrolithiasis in children has been reported to increase by approximately
6-10% annually, and the incidence is currently 50 per 100,000 children with high recurrent
rate. Investigators aimed to determine the metabolic risk factors in Chinese children
through metabolic evaluation.
In order to identify diagnostic criteria of hypocitraturia and hyperoxaluria in western
country wether adapt to Chinese children, investigators aim to determine ... Read More
Source: Charles Drew University of Medicine and Science
This study investigates the degree of improvement in insulin resistance and features of the
metabolic syndrome in non-diabetic overweight or obese subjects after training in a
low-intensity, moderate-intensity or non-aerobic exercise program, as well as self-initiated
exercise behavior after the assigned exercise program.
Source: Institute for Clinical and Experimental Medicine
The aim of the study is to evaluate the effect of metformin on myocardial function, insulin
resistance and selected metabolic markers in patients with type 2 diabetes and heart failure
(HF+DM+) in a cross-over, randomized, placebo controlled trial.
Metformin treatment in HF+DM+ group will lead to better myocardial function and load
tolerance in comparison to placebo. The degree of improvement will be linked to selected
metabolic ... Read More
: Although intervention or prevention with young children with T1DM may help ameliorate
problems or forestall later problems in metabolic control, a number of potential barriers to
research have constrained the development of such interventions. To assess the feasibility
of intervening with young children and their families, we propose to conduct an exploratory
pilot study of a behavioral intervention for young children (ages 7 to 11) newly diagnosed
with ... Read More
Source: Norwegian University of Science and Technology
The primary objective of the study is to compare in a real-world setting the efficacy of
traditional training (today's guideline, vigorously or moderate exercise) and amount of
aerobic interval training (1-AIT) in reduction of risk factors constituting metabolic
The secondary objective is to compare the efficacy of traditional moderate training (today's
guideline) and amount of aerobic interval training (1-AIT vs. 4-AIT) in improving aerobic
... Read More
The purpose of this study is determine the incidence of metabolic syndrome (MetS) in people
of high risk, of 40 or more years and attended in the Primary Care. Evaluating the
association between anxiety, depression, quality of life and the vital stressful events, and
the development of the metabolic syndrome in general population.
Our hypothesis is that population of the cohort with bigger degree of stress will develop
earlier the metabolic syndrome.
... Read More
The study is designed to answer the following questions:
1. Is hypogonadism a cause for the metabolic syndrome ?
2. What is the effect of testosterone replacement on the metabolic parameters ?
Follow-up of two hospital-based patient cohorts (heart failure, metabolic comorbidities in
CVD), recruited at baseline by the GANI_MED-project (Greifswald Approach to Individualized
Medicine). Standardized protocols will be used for the assessment of medical history,
laboratory biomarkers, and the collection of various biosamples for bio-banking purposes.
Comparisons with the general background population will be performed.
Metabolic syndrome (MS) has been reported as a risk for cardiovascular events. The aim of
the present cohort study is to investigate whether ACEi therapy reduces the rate of
periprocedural myocardial injury (PPMI) after elective percutaneous coronary intervention
(PCI) among patients with metabolic syndrome.
The investigators will conduct a cross-sectional study to discovery the distribution of IBS
subtypes who would like to seek TCM treatment and their TCM patterns. At the same time, the
investigators will also collect the serum, urine and stool samples of the participants to
explore the host-gut microbiota metabolic interactions associated with IBS subtypes.
We are testing the safety and efficacy of a 16-wk yoga lifestyle intervention on oral
glucose tolerance, fasting lipid/lipoprotein levels, body composition, cardiovascular
function, quality of life, CD4+ T-cell counts and viral load in HIV-infected men and women
with components of The Metabolic Syndrome. We hypothesize that a yoga lifestyle intervention
will improve metabolic, anthropometric, cardiovascular disease parameters, and quality of
life domains ... Read More
Source: Northeastern Ohio Universities College of Medicine
The purpose of this study is to evaluate the efficacy of topiramate compared to placebo in
the treatment of obesity in metabolic syndrome. Secondary objectives include topiramate and
weight loss effects on lipid levels, HbA1C, insulin resistance, and blood pressure.
Amylose-amylopectin ratio may influence the rate of starch digestion. This randomized
controlled study evaluated the postprandial metabolic effects of amylose-rich- wheat- based
rusks in overweight subjects.