To improve the clinical care of women with pelvic pain and abnormal uterine bleeding due to
benign uterine conditions including leiomyomas (uterine fibroids) and adenomyosis by
evaluating the accuracy of radiology diagnostic exams (MRI(magnetic resonance imaging),
ultrasound and ultrasound with elastography).
The primary aim of this study is to fully test a culturally/religiously-tailored,
church-based HIV screening intervention (TIPS) against a standard HIV information
intervention on HIV screening rates at 6 and 12 months with adult African American church
members and community members who use church outreach services. Our secondary outcome is to
reduce sexual risk behaviors with this same population.
i) The primary objective of this study is to determine if physical therapy improves
postoperative quality of life in participants following vaginal reconstructive surgery for
pelvic organ prolapse and urinary incontinence.
ii) Secondary objectives include:
1. Comparing pelvic floor symptoms (urinary symptoms, defecatory symptoms and prolapse
symptoms) in participants undergoing physical therapy compared to standard
... Read More
This is a multi-center exploratory study (each site got local IRB approval) of the impact of
an educational toolkit combined with a practice-performance self-evaluation instrument (ABIM
Care of the Vulnerable Elderly Practice Improvement Module) on trainee knowledge, skills,
and attitudes about practice-based learning and improvement and systems-based practice in
the care of elderly patients.
The purpose of this study is to determine whether a modified behavioral treatment for weight
loss that includes one-on-one treatment for individuals struggling to lose weight is
associated with more weight loss than a standard behavioral treatment.
This is a randomized, open-label, controlled, multicenter, Phase III study. Patients will be
randomly assigned to treatment group (1:1) through a dynamic randomization process with use
of the following stratification factors: sex (female/male), disease stage (stage IIIb vs.
stage IV vs. recurrence), and EGFR gene mutation (exon 19 deletion vs. exon 21 L858R).
This study seeks to establish the effect of regular structured feedback on surgical
performance using crowd sourced video assessments with validated objective performance
scores and time to complete a specific surgical procedure through a randomized controlled
trial. The working hypothesis is that regular structured assessment will lead to a greater
measurable improvement in performance, as defined by objective performance scores, than will
traditional ... Read More
Source: National Institutes of Health Clinical Center (CC)
The Hematology Service provides hematology consultations for patients at the Clinical Center
and participates in the training of hematology fellows. Patients with a broad range of
hematologic disorders must be available in order for the senior staff of the Service to
maintain clinical expertise and to provide the breadth of experience necessary for the
fellowship program. The purpose of this protocol is to meet these needs by allowing the
Hematology Service ... Read More
The North American Scapula Consortium (NASCon) is a multi-center injury specific outcomes
There currently exists a paucity of outcomes data in the literature on this patient
population. The NASCon registry will be a resource in which investigators can conduct
adequately powered clinical outcomes research resulting in higher quality research with
meaningful results, improved patient care, and evidence-based advancement for the treatment
of ... Read More
The purpose of this study is to evaluate the diagnostic performance of three Tesla magnetic
resonance imaging (3T MRI) compared to magnetic resonance arthrogram (MR arthrogram) in
diagnosing superior labrum anterior posterior (SLAP) lesions. We hypothesize that 3T MRI
will have non-inferior sensitivity compared to MR arthrogram in diagnosing SLAP lesions
utilizing arthroscopy as our gold standard test. To evaluate our hypothesis, the
investigators will ... Read More
This research is being done to learn more about patient experiences at the Johns Hopkins
Rheumatology Clinic at Good Samaritan Hospital. We want to learn about the patient, his or
her health and experience with the doctor. Up to 75 patients (21 years and older) who are
seen in this clinic may participate.
Source: International Agency for Research on Cancer
The primary study hypothesis is that a two-dose human papillomavirus (HPV) vaccine regimen
would offer similar immunogenicity and protection as that of a three-dose regimen to girls
against persistent HPV infection and cervical neoplasia caused by HPV types included in the
The purpose of this study is to assess study subjects' adherence to different weight control
intervention programs and the effect of intervention programs on physical and biochemical
examinations, physical fitness, food intake and exercise behaviors and the prevalence of
metabolic syndrome and its components' abnormalities.
The purpose of the proposed trial is to determine whether contrast-enhanced ultrasound
(CEUS) can be used to assess the recurrence of renal cell carcinoma (RCC) after cryoablation
compared to contrast enhanced CT or MR (the standard evaluation). This study involves the
off-label use of an FDA-approved ultrasound contrast agent, Optison that flows in the
vascularity. CEUS will be performed by both two and three dimensional ultrasound to examine
... Read More
The investigators will conduct a prospective observational cohort study to investigate
factors that influence contraceptive method utilization among women with medical conditions.
The investigators will also investigate how women with medical conditions access to
contraception and family planning fellowship trained specialist. After the baseline
questionnaire, there be a 3 month and 6 month follow up questionnaire to investigate
continuation and satisfaction ... Read More
Building on an earlier pilot study, this randomized controlled trial will compare the
effectiveness of a 12 week community YMCA-based wellness program specifically designed for
people with stroke (Fit for Function) to a standard YMCA membership.
Objective: To conduct a pilot randomized controlled trial comparing the effectiveness of a
parent support intervention consisting of periodic text messages and educational support
(video, collateral materials),and usual care on the healthcare engagement of limited English
proficient (LEP) Latino parents during their child's first year and to examine its impact on
healthcare utilization and primary care quality.
The New Hampshire Medicaid Wellness Incentive Program (WIP) will address both the health
disparity and increased costs by providing incentivized health promotion programs to
overweight or obese and/or tobacco-smoking Medicaid beneficiaries receiving services at New
Hampshire's 10 regional Community Mental Health Centers (CMHCs).
Background: Laparoscopic Roux en Y gastric bypass (LRYGB) is associated with a significant
learning curve. We report the results of a systematic training programme from a high volume
bariatric center measuring the outcome by comparing the results with data from a consecutive
series of 1000 fast track LRYGB.
Method: Using a stepwise training programme the RY gastric bypass operation was divided into
an upper and lower procedure and subdivided into 11 well ... Read More
Hypothesis: ACE tool for colonoscopy and EGD allows for reliable standardized learning
curves, competency benchmarks, and creation of a centralized database that compares trainee
performance amongst peers. Trainees receiving quarterly learning curves achieve competence
in endoscopic procedures at a faster rate (ie less procedures) compared to trainees
receiving usual feedback on endoscopic performance as established by their respective GI
fellowship ... Read More