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Clinical Trials: Intensive Care Medicine

Source: Kompetenznetz Sepsis
Severe sepsis and septic shock are diseases of infectious origin with a high risk of death. Antibiotic therapy is mandatory but it is unknown whether one antibiotic alone is sufficient for initial therapy. The purpose of this study is to compare a therapy with meropenem alone or the combination of meropenem plus moxifloxacin in the treatment of severe sepsis/ septic shock. Patients randomly receive one of the two treatments for at least 7 days but not longer ... Read More
Last Updated: 27 Jun 2012
Source: Kompetenznetz Sepsis
Severe sepsis and septic shock are diseases of infectious origin with a high risk of death. The purpose of this study is to determine whether the intravenous application of selenium (given as sodium-selenite) can reduce mortality in patients with severe sepsis or septic shock. Additionally, it is investigated, whether the measurement of procalcitonin - a marker of infection - can be used to guide anti-infectious measures in this disease. Read More
Last Updated: 10 Aug 2016
Source: Universitätsklinikum Hamburg-Eppendorf
The study aimed to compare CT-based virtual autopsy with classic autopsy as a tool for quality control in intensive care medicine. Read More
Last Updated: 15 Jun 2015
Source: Charite University, Berlin, Germany
One goal of the investigators of the Department of Anesthesiology and Intensive Care Medicine CVK/CCM, Charité - University Medicine Berlin is a continuous improvement in the quality of care to the patients. One focus is the freezing preoperatively during surgery, and on the follow-up study to assess the perceived waiting times in the anesthesiology outpatient clinic. The project aims to quality assurance and quality improvement of the Department of ... Read More
Last Updated: 31 Jul 2016
Source: Charite University, Berlin, Germany
Medication errors are common in intensive care (Valentin A et al., BMJ. 2009;338). Standardized color coded labels for user applied syringes enjoy strong support from many health professionals, thinking that this might increase patient safety. Whether this is true or not warrants further research. Read More
Last Updated: 29 Oct 2015
Source: University Hospital, Geneva
This study will evaluate the ease of use of the new calorimeter (Quark RMR 2.0 (COSMED, Italy)) in intensive care unit (ICU) patients compared to currently used calorimeters (i.e. Quark RMR 1.0(COSMED, Italy) or Deltatrac Metabolic Monitor (Datex, Finland)), as well as the stability and the feasibility of the measurements in various clinically relevant situations. Time needed to prepare and start indirect calorimetry (IC) measurement will be compared as ... Read More
Last Updated: 05 Jun 2016
Source: University of Aarhus
The purpose of this study is to determine if 48 hours of mild therapeutic hypothermia following out of hospital cardiac arrest gives a better cerebral outcome compared to 24 hours therapeutic hypothermia. Read More
Last Updated: 16 Jan 2017
Source: Charite University, Berlin, Germany
A goal directed , demand-driven administration of sedative drugs is an integral part of every intensive care treatment. During long-term application of sedatives, Midazolam is the most commonly used sedative in Europe. One major objective is the problem of oversedation and agitation during an intensive care treatment due to the lack of controllability of available substances. The Love-Mi RCT investigates the clinical controllability of Midazolam versus the ... Read More
Last Updated: 14 Sep 2016
Source: Charite University, Berlin, Germany
Description of the decision making process as well as the practices of end of life care in an ICU of a German university hospital during the period when changes of German legislation occurred. Read More
Last Updated: 09 Feb 2011
Source: Japanese Society of Intensive Care Medicine
The purpose of this multination multicenter observational study is to determine the impact of fever and antipyretic on outcomes in critically ill patients. Read More
Last Updated: 17 May 2010
Source: Johann Wolfgang Goethe University Hospital
Evaluation if physostigmine reduces symptoms in patients who has developed a delirium in Intensive care after a surgery Read More
Last Updated: 10 Aug 2014
Source: University Hospital Muenster
The aim of this study is to evaluate the effect of regional citrate anticoagulation within the scope of continuous renal replacement (CRRT) in critically ill patients with acute kidney injury (AKI) on filter life span and 90-day all cause mortality. Read More
Last Updated: 13 Nov 2016
Source: Charite University, Berlin, Germany
In this prospective, multicenter observational study the investigators capture the perioperative course of peripheral cholinesterase activity. The focus is the perioperative inflammation causing postoperative delirium. Therefore we measure the activity of Acetylcholine-Esterase and Butyrylcholine-Esterase in whole blood of adults in the perioperative context. Early postoperative delirium will be detected by Nu-DESC in the Recovery Room or the ... Read More
Last Updated: 08 Aug 2016
Source: Royal College of Anesthesiologists of Thailand
- Overall treatment outcomes of University base SICU - Incidence of adverse events in SICU - Factor associated to adverse events in SICU Read More
Last Updated: 19 May 2011
Source: University Hospital Tuebingen
This observational clinical study investigates cellular and plasmatic activation markers as well as proteins involved in coagulation and inflammation in patients being connected to different extracorporeal circulation (ECC) and circulatory support devices under intensive care conditions. Read More
Last Updated: 30 Oct 2016
Source: Anbics Management-Services Ag
The purpose of this study is to assess the clinical efficacy of azithromycin, used as a quorum-sensing blocker, when compared to placebo for preventing or delaying the occurrence of pneumonia in ventilated patients colonized with Pseudomonas aeruginosa. Read More
Last Updated: 27 Jan 2008
Source: Providence Health & Services
The purpose of this study is to determine whether reducing intern work hours and eliminating extended shifts in the intensive care unit will reduce prescribing errors and improve intern well-being. Read More
Last Updated: 14 Oct 2009
Source: Technische Universität Dresden
In Intensive Care Medicine, critical incidents are not rare and may result in fatal outcome. High fidelity patient simulators are commonly used in training curricula for healthcare professionals especially in anesthesiology, emergency medicine, and intensive care medicine. Several different course concepts have previously been published. As we know from recently published data, up to 80% of all critical incidents in the field of medicine are caused by human ... Read More
Last Updated: 24 Jun 2008
Source: Katholieke Universiteit Leuven
In a previous study, the investigators showed that tight blood glucose control with insulin during intensive care reduced morbidity and mortality in adult intensive care patients. Whether this intervention also improves prognosis of pediatric intensive care patients remains unknown. The current prospective, randomized, controlled study will asses the impact of intensive insulin therapy on outcome of patients in a pediatric intensive care unit. On admission ... Read More
Last Updated: 23 Aug 2011
Source: Universitätsklinikum Hamburg-Eppendorf
The aim of the study is to compare findings generated by CT-based autopsy (Virtopsy) with conventional autopsy and clinical diagnoses. Therefore all patients dying while receiving treatment in the Department of Intensive Care Medicine will be undergo virtopsy and, if relatives give informed consent conventional autopsy. Read More
Last Updated: 27 May 2015
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