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Clinical Trials: Infectious Disease


Source: Drug Induced Liver Disease Study Group
This is a multi-center, open-enrollment, retrospective, non-interventional epidemiologic study without any clinical treatment. Its primary objective is to understand 1) incidence of drug-induced liver injury, including incidences among all the hospitalized patient, among patients in department of hepatic diseases, digestive diseases, oncology, hematology etc., individually; 2) epidemiologic characteristics of drug-induced liver injury, including suspected ... Read More
Last Updated: 23 Oct 2016
Source: Memorial Sloan Kettering Cancer Center
The purpose of this study is to determine if an infectious disease may be associated with the new lymphoma diagnosis. Infections to be tested include: 1. Helicobacter pylori (H. pylori): This is a bacteria sometimes found in the stomach that has been associated with a particular kind of lymphoma, gastric MALT. We are interested to learn if the H. pylori infection may be associated with other indolent lymphomas. 2. Hepatitis C: This ... Read More
Last Updated: 12 Aug 2014
Source: National Institute of Allergy and Infectious Diseases (NIAID)
Cytomegalovirus (CMV) infection is known to cause hearing loss and mental retardation. The purpose of this study is to compare a 6-week course to a 6-month course of the drug valganciclovir in babies born with CMV to assess the safety and efficacy of this treatment. Participants will include 104 infants (30 days old or younger) born with CMV disease. All infants will take valganciclovir by mouth for 6 weeks. At the end of the 6 week period, subjects will be ... Read More
Last Updated: 12 Aug 2015
Source: National Institute of Allergy and Infectious Diseases (NIAID)
A common group of viruses that infect humans are enteroviruses. Enteroviruses produce illnesses in children which may range from very mild (summer colds) to severe (infections of the brain, liver, and heart). The purpose of this study is to determine if a new drug called pleconaril helps treat babies with enteroviral sepsis. In addition, researchers are attempting to determine a safe and effective dose of pleconaril to help babies with this disease. Infants ... Read More
Last Updated: 27 Feb 2013
Source: Servier
The objective of this study is to evaluate long-term safety of gevokizumab in patient with chronic non-infectious uveitis who previously well tolerated the study drug and may benefit from longterm treatment with gevokizumab. Read More
Last Updated: 14 Oct 2015
Source: HaEmek Medical Center, Israel
Sepsis related to the development of cardiac complications. However, the investigators understanding regarding this condition remains incomplete. Possible explanations raised include coronary perfusion decrease, activation of the coagulation system and release of inflammatory mediators, including endotoxins, cytokines and others. In this study the investigators wanted to examine the impact of any infectious disease, (not necessarily Pneumonia), on the QT ... Read More
Last Updated: 08 Nov 2016
Source: Pathoquest
The study patients are patients suffering from primary or secondary immunodeficiencies investigated in the Hospital Necker for a suspected infectious disease. The study purpose is to assess the performance of a High Throughput Sequencing method, the PATHOQUEST method (from sample preparation to bio informatic analysis), versus the classic diagnostic approach. The study will evaluate the capacity of the PATHOQUEST method to detect pathogens ... Read More
Last Updated: 19 Apr 2015
Source: NIH AIDS Clinical Trials Information Service
The purpose of this study is to determine the effect of treatment with Trizivir (TZV) plus efavirenz (EFV) or TZV alone on viral load (level of HIV in the blood). Read More
Last Updated: 22 Jun 2005
Source: Dünyagöz Hospital
This study evaluates the significance of differences in serum angiotensin converting enzyme and lysozyme levels of patients with ocular involvement of other autoimmune inflammatory and infectious diseases. Read More
Last Updated: 08 Dec 2015
Source: Karius, Inc.
Prospective study at Duke University Hospital comparing the Karius Infectious Disease Diagnostic Sequencing Assay to blood culture results in admitted patients with bacteremia/septicemia. Read More
Last Updated: 06 Dec 2016
Source: Gilead Sciences
This protocol describes a prospective, randomized, open-label, multicenter study to evaluate the safety and efficacy of switching from fixed dose abacavir (ABC)/lamivudine (3TC) to fixed dose emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) in virologically suppressed, human immunodeficiency virus type 1 (HIV-1) infected subjects maintained on a ritonavir-boosted protease inhibitor (PI/r)-containing antiretroviral (ARV) regimen. Duration of treatment ... Read More
Last Updated: 21 May 2012
Source: National Institute of Allergy and Infectious Diseases (NIAID)
Adults admitted to intensive care units are at risk for a variety of complications. One of the most frequent complications is the development of new infections. Infections due to a fungus called Candida are of particular concern. This study will test the possibility that caspofungin, a new therapy for fungal infections, may reduce the rate of Candida infections in subjects at risk. Read More
Last Updated: 03 Dec 2014
Source: China Academy of Chinese Medical Sciences
The study is aimed to evaluate the effectiveness and safety of Jinlianqingre Effervescent Tablets, a traditional Chinese medicine (TCM), in the treatment of Uncomplicated hand, foot, and mouth disease (HFMD). Read More
Last Updated: 15 Jan 2013
Source: Evandro Chagas National Institute of Infectious Disease
Due to the lack of information in the literature about the role of cardiac rehabilitation on Chagas heart failure, the aim of the present study was to evaluate the effects of a cardiac exercise program on functional capacity, cardiac function, respiratory muscle strength, body composition, biomarkers and quality of life among Chagas heart failure patients. Read More
Last Updated: 02 Aug 2015
Source: National Institute of Allergy and Infectious Diseases (NIAID)
The purpose of this study is to collect blood samples from HIV infected individuals for use in future genetic studies. Read More
Last Updated: 15 May 2014
Source: Karius, Inc.
Prospective, observational study at Stanford University Hospital comparing the Karius Infectious Disease Diagnostic Sequencing Assay to the final microbiologic diagnosis in patients with fever and neutropenia. Read More
Last Updated: 19 Sep 2016
Source: ViiV Healthcare
To provide access to maraviroc to patients who have limited or no therapeutic treatment options and to collect more safety data in a broader patient population. Read More
Last Updated: 22 May 2016
Source: National Institutes of Health Clinical Center (CC)
Background: - Increased clinical attention has been paid to the evaluation and management of bioterrorism-related illness (such as anthrax infection) and emerging infectious diseases (such as Severe Acute Respiratory Syndrome [SARS] and new strains of influenza). However, evaluation and treatment data for these illnesses are often limited because human infections to date have been relatively limited. Further knowledge about diseases of bioterrorism ... Read More
Last Updated: 23 Jan 2017
Source: Gilead Sciences
This study is to evaluate the safety and tolerability of cobicistat-boosted darunavir plus two fully active nucleoside analogue reverse transcriptase inhibitors in HIV 1 infected, antiretroviral treatment-naive and treatment-experienced adults with no darunavir (DRV) resistance-associated mutations. After the Week 48 Visit, participants will be given the option to participate in an open-label rollover phase to receive cobicistat and attend visits every 12 ... Read More
Last Updated: 25 Oct 2016
Source: XOMA (US) LLC
The purpose of this study is to evaluate the efficacy of gevokizumab in reducing the risk of recurrent uveitic disease in subjects with non-infectious uveitis whose disease is currently controlled with systemic treatment. Read More
Last Updated: 10 Jul 2016
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