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Clinical Trials: General Medicine

Source: University of British Columbia
Miscommunication during patient handover can jeopardize patient safety and is the focus of Quality Improvement initiatives by many organizations. It is widely recognized that such miscommunication is preventable using a number of strategies identified in the literature. Currently, there is no formal handover process of General Internal Medicine in-patients, otherwise known as the Clinical Teaching Unit (CTU) at Vancouver General Hospital, which is a major ... Read More
Last Updated: 13 Jan 2016
Source: Nanotherapeutics, Inc.
The purpose of this observational study, which will be initiated as soon as the licensed H1N1 Pandemic Influenza Vaccine is used in a mass vaccination campaign, is to estimate the incidence of any medically-attended adverse events in all vaccinated subjects. Read More
Last Updated: 06 Oct 2015
Source: Translational Research Informatics Center, Kobe, Hyogo, Japan
RATIONALE: Drugs used in chemotherapy, such as tegafur-uracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving chemotherapy after surgery may kill any tumor cells that remain after surgery. Sometimes, after surgery, the tumor may not need more treatment until it progresses. In this case, observation may be sufficient. It is not yet known whether chemotherapy is more effective ... Read More
Last Updated: 25 Sep 2016
Source: Translational Research Informatics Center, Kobe, Hyogo, Japan
RATIONALE: Studying samples of tumor tissue in the laboratory from patients with cancer may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict which patients will respond to treatment. PURPOSE: This laboratory study is looking at prognostic factors in patients receiving tegafur-uracil for stage II colon cancer that was completely removed by surgery. Read More
Last Updated: 25 Sep 2016
Source: Chengdu PLA General Hospital
To evaluate the compliance of traditional Chinese medicine (TCM) in young people with Chronic rheumatic disease Read More
Last Updated: 15 Aug 2015
Source: Shire
The purpose of this study is to proof increasing patient satisfaction and preservation of quality of life in patients with Morbus Fabry disease receiving their Enzyme Replacement Therapy with Replagal (Agalsidase alfa) at home compared to receiving the infusions at the clinic or at doctor's practice. Read More
Last Updated: 08 May 2016
Source: Singapore General Hospital
The purpose of this study is to study the efficacy of Traditional Chinese Medicine (TCM) on anaemic and cytopenic haematological disorders including myelodysplastic syndrome (MDS), aplastic anaemia (AA), myelofibrosis (MF) and thalassemia intermedia who do not have or did not respond to available treatment options. Read More
Last Updated: 13 May 2012
Source: Chinese PLA General Hospital
-Evaluate the efficacy and safety of Shenyankangfu Tablets to control the proteinuria of patients with primary glomerulonephritis compare with Losartan potassium. Read More
Last Updated: 28 Jun 2015
Source: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
A Prospective Study on the Efficacy and Safety of CD8+NKG2D+ AKT cell immunotherapy to the pancreatic cancer patients treated with adjuvant chemotherapy. Read More
Last Updated: 09 Oct 2016
Source: University of Athens
To develop a score that can predict early from diagnosis of Clostridium difficile infection (CDI) the risk for relapse and of unfavorable outcome. This score can be used in the future to identify patients will benefit from fidaxomicin treatment. Read More
Last Updated: 30 Oct 2016
Source: Icahn School of Medicine at Mount Sinai
Patients who on taking clopidogrel are randomized to either continue clopidogrel into general surgery or discontinue clopidogrel 7 days before surgery. All patients resume clopidogrel after surgery. The investigators track the development of bleeding complications that may develop within 90 days of the surgery. Patients are medically cleared to be in either arm of the study by their cardiologist and surgeon. There is currently no evidence to support for or ... Read More
Last Updated: 03 Nov 2015
Source: Associations for Establishment of Evidence in Interventions
A prospective multicenter registry in real-world Japanese patients undergoing DAPT for three months after stenting. To assess the long-term safety of Endeavor Zotarolimus-eluting stent through noninferiority in the primary endpoint between two different continuous regimen (three and twelve months) groups of DAPT after stenting with Endeavor Zotarolimus-eluting stent in real-world Japanese patients and to examine the optimal duration of DAPT after stenting ... Read More
Last Updated: 04 Jan 2016
Source: Centre Hospitalier Universitaire de Nīmes
The main objective of this study is to evaluate the inter-observer concordance when measuring the maximum value of the external antero-posterior diameter of the sub-renal aorta (both cross-sectional and longitudinal ultrasound views are measured). The first measure is made by a general practitioner in private practice; second reading are made by an expert in vascular medicine. Read More
Last Updated: 01 Aug 2016
Source: National Taiwan University Hospital
The trial is aimed to show that implementation of a procalcitonin-guided antibiotics algorithm may result in shortened antibiotics course in ICU sepsis patients without inferior outcome as compared to the conventional therapy Read More
Last Updated: 25 Nov 2012
Source: Chinese PLA General Hospital
Huangkui Capsule is a single medicament of traditional Chinese medicine consists of Abelmoschus manihot and has been widely used to treat kidney disease. The purpose of this study is to evaluate the safety and efficacy of Abelmoschus manihot for treating chronic kidney disease in large scale samples with long time take. Read More
Last Updated: 30 May 2016
Source: University Medicine Greifswald
The aim of the investigation is to validate the SmartPhone-based 4-Reaction Choice Time Test (4CRT) as a measure for recovery of the psychomotor function in patients after general anesthesia. One hundred female patients, scheduled to ambulatory gynecological surgery in general anesthesia, will be randomized to the group with pharmacological anxiolytic premedication with midazolam (N=50) and to the group without midazolam (N=50). All patients will be ... Read More
Last Updated: 26 Jun 2016
Source: University of Schleswig-Holstein
Prospective, bicentric observational study to assess a novel system for automated control of mechanical ventilation (Smart Vent Control, SVC) during general anesthesia. Read More
Last Updated: 29 Dec 2015
Source: Shire
A double-blind, randomized, controlled trial comparing the safety and effectiveness of conventional therapy with ecallantide to conventional therapy with placebo. Read More
Last Updated: 27 Jun 2016
Source: Mebix Inc
The purpose of this study is to investigate the non-inferiority of bisoprolol to carvedilol by evaluating tolerability (The probability that administered maintenance dose reaches the maximum will be determined as an indicator) as a primary endpoint when bisoprolol or carvedilol is administered for 48 weeks to Japanese chronic heart failure patients. In addition, the safety and efficacy of bisoprolol will be investigated. Read More
Last Updated: 09 May 2014
Source: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Combined with the clinical data of FK506 and the database of GO and Kyoto Encyclopedia of Genes and Genomes(KEGG), the investigators aim to carry out the bioinformatic analysis and build a muti-locus genetic model, then muti-center assess the predictive accuracy of FK506 metabolic differences. Read More
Last Updated: 27 Apr 2016
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