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Clinical Trials: Colorectal Surgery

Source: National Cancer Center, Korea
In colorectal surgery, the use of prophylactic antibiotics is recommended. The standard use of antibiotics for colorectal surgery is three doses. It has been reported that the surgical site infection rates of laparoscopic colorectal surgery are lower than open colorectal surgery. However, the evidence of proper application of antibiotic for laparoscopic colorectal surgery is still not enough. The investigators are researching the efficacy and safety of one ... Read More
Last Updated: 10 Dec 2011
Source: Assistance Publique - Hôpitaux de Paris
Rehabilitation program improves operative results following conventional open colorectal surgery. Very few data are available on such program in laparoscopic colorectal surgery. Read More
Last Updated: 17 Aug 2016
Source: University of Surrey
To ascertain whether there are fewer adhesions (internal scars) formed following laparoscopic (key-hole) surgery for colorectal diseases than traditional open surgery. Read More
Last Updated: 12 Sep 2007
Source: University of California, Irvine
This is a prevalence study evaluating lower urinary tract, prolapse, bowel, and sexual symptoms in women with a colorectal disorder who are planning to undergo surgery. The purpose of this study is to identify the number of women who complain of lower urinary tract and bowel problems, including frequency, urgency, urinary incontinence, fecal incontinence, pain with intercourse, and other sexual problems prior to undergoing surgical management for a ... Read More
Last Updated: 12 Jul 2010
Source: Japan Multinational Trial Organization
The purpose of this study is to determine optimal prophylactic antibiotics administration method in elective laparoscopic colorectal surgery. Read More
Last Updated: 17 Sep 2012
Source: University of Surrey
Hypothesis: The total costs of laparoscopic colorectal surgery are less than those of open surgery. Secondary hypothesis: Patients quality of life is higher following laparoscopic surgery, as compared to open colorectal surgery. Research objectives: 1. To estimate the cost implications and clinical benefits of incorporating laparoscopic colorectal surgery into routine clinical practice. 2. To examine whether the increased operative ... Read More
Last Updated: 15 Apr 2009
Source: University Hospital, Geneva
Anastomotic leak is a devastating complication of colorectal surgery. There is no widespread means of assessing the viability of a laparoscopic anastomosis. The investigators described recently the feasibility of microvascularisation assessment with near-infra red technology (NIR). The aim of this study is to look at the implementation of this technique in a wider prospective series of patients undergoing colorectal resection. Read More
Last Updated: 31 May 2015
Source: Universität Duisburg-Essen
This study aims to test the effects of a Preoperative Relaxation intervention and an Intensified Surgery Patient Education on pre- and postoperative wellbeing and health in Patients Undergoing colorectal surgery. Read More
Last Updated: 26 Oct 2016
Source: Fudan University
The purpose of this study is to determine whether ERAS is safe and can decrease surgical stress, increase functional recovery and reduce complication rate in colorectal surgery. Read More
Last Updated: 23 Mar 2009
Source: First Hospital of Jilin University
To compare the outcomes of fast track laparoscopic surgery and conventional laparoscopic surgery. Read More
Last Updated: 20 Oct 2013
Source: University Hospitals Cleveland Medical Center
The purpose of this study is to produce a user-friendly tool- in the form of a questionnaire - to accurately assess early quality of life in patients after abdominal colorectal surgery from the first day after surgery to 6 months after. The study will also compare this questionnaire to the other currently available assessment tools. Patients are invited to participate if they are undergoing abdominal colorectal surgery at University Hospitals of Cleveland. ... Read More
Last Updated: 11 Dec 2014
Source: Huazhong University of Science and Technology
The purpose of this study is to verify the 5-year disease free survival (DFS) of resectable colorectal cancer after laparoscopic surgery according to a Chinese Operative Standard was not inferior to open surgery. Read More
Last Updated: 22 Sep 2014
Source: Instituto de Investigación Hospital Universitario La Paz
A comparison of skin closure techniques (standard skin closure with staples versus a continuous (subcuticular) absorbable suture), to determine if this changes the rate of post operative wound infections in elective colorectal surgery patients. Read More
Last Updated: 19 May 2014
Source: Mayo Clinic
This study will assess if administration of a loop diuretic, specifically furosemide, to achieve euvolemia can safely reduce length of stay following colorectal surgery. Read More
Last Updated: 19 Apr 2016
Source: University of Arkansas
The Enhanced Recovery After Surgery system for perioperative care of patients undergoing major abdominal surgery, particularly colorectal surgery, was formed in Europe by a surgeon named Henrik Kehlet in 1994. Dr. Kehlet observed that his patients undergoing colorectal surgery were hospitalized postoperatively for extended periods of time due to prolonged return of the normal intestinal physiology and of other bodily functions. He formulated a system of ... Read More
Last Updated: 18 Dec 2016
Source: Ikazia Hospital, Rotterdam
Mechanical bowel preparation (MBP) is common practice in elective colorectal surgery. In recent literature the value of MBP is subject of discussion. We conducted a multicenter, randomized study with the goal of comparing outcome of elective colorectal resections and primary anastomoses with and without mechanical bowel preparation in terms of anastomotic leakage and other septic complications. Within the setting of a multicenter randomized trial,1433 ... Read More
Last Updated: 06 Feb 2006
Source: Chinese University of Hong Kong
Background: Our previous study demonstrated that electroacupuncture at Zusanli, Sanyinjiao, Hegu, and Zhigou reduces the duration of postoperative ileus and hospital stay after laparoscopic colorectal surgery within a traditional perioperative care setting. Recent evidence also suggested that a 'fast-track' perioperative program may help accelerate recovery after colorectal surgery. As electroacupuncture is simpler to implement and less labor intensive, it ... Read More
Last Updated: 09 Feb 2014
Source: National Institutes of Health Clinical Center (CC)
Background: - Some types of inflammation may increase the risk of cancers in the intestinal track. Because of this possibility, anti-inflammatory drugs may be able to prevent tumor growth and spread. One such drug, sulindac, may be helpful to study. Researchers want to see if people who are having surgery to remove intestinal tumors from advanced colorectal cancer will benefit from sulindac. It will be tested against a placebo. Objectives: - ... Read More
Last Updated: 21 Oct 2015
Source: Nanfang Hospital of Southern Medical University
- Compared with traditional open colectomy, laparoscopic surgery is associated with less pain, earlier recovery, and better cosmetic outcome, and its short- and long-term oncologic outcomes have been demonstrated. - In experienced surgeons' hands, single incision laparoscopic surgery is increasingly performed for colorectal disease, and even for malignant lesion because of its reduced incision-associated morbidity and scarring. ... Read More
Last Updated: 16 Apr 2014
Source: Kangbuk Samsung Hospital
The purpose of this study is to determine whether intravenous lidocaine increase the tolerability of early oral feeding after laparoscopic colorectal surgery in patients with colorectal cancer. - Degree of nausea/vomiting. - Degree of postoperative pain and opioids requirement. - Time to first flatus, time to first stool, time to tolerance of regular diet, rate of postoperative complications and duration of postoperative hospital ... Read More
Last Updated: 14 Oct 2012
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