The purpose of the study is to acquire additional data on safety and tolerability of
recombinant human hyaluronidase (rHuPH20) facilitated subcutaneous treatment of Immune
Globulin Infusion (Human), 10% (IGI, 10%) and to assess the mode of product administration.
The purpose of the proposed study is to acquire additional data (including the assessment of
anti-rHuPH20 antibodies) on the long-term safety of HYQVIA and to assess the prescribed
treatment regimens and treatment administration in routine clinical practice.
This study is being conducted to confirm the efficacy, safety, and immunogenicity of
recombinant human C1 inhibitor (rhC1INH) at a dose of 50 U/kg when used for the treatment of
acute angioedema attacks in Hereditary Angioedema (HAE) patients.
To evaluate the efficacy of recombinant human C1 inhibitor (rhC1INH) in the prophylaxis of
angioedema attacks in patients with HAE
To evaluate the safety and immunogenicity of recombinant human C1 inhibitor (rhC1INH) in the
prophylaxis of angioedema attacks in patients with HAE
RATIONALE: Studying samples of blood or tumor tissue from patients with cancer in the
laboratory may help doctors identify and learn more about biomarkers related to cancer.
PURPOSE: This clinical trial studies prostate-specific antigen (PSA) antibody levels in
samples from patients treated for prostate cancer on trial ECOG-E9802.
The objective of this study is to evaluate the formation of antibodies, the occurence of
allergic reactions, and the risk of hypercoagulability and hypocoagulability in patients
treated with KALBITOR (ecallantide).
This study is being conducted to explore the clinical safety, local tolerability,
convenience and effectiveness of self-treatment of hereditary angioedema (HAE) attacks with
subcutaneous injections of icatibant.
Source: NIH AIDS Clinical Trials Information Service
To confirm results from a previous study in which the combination of thymopentin plus
zidovudine ( AZT ), an antiretroviral agent, slowed disease progression in HIV-infected
asymptomatic patients. To evaluate the efficacy and safety of thymopentin in HIV-infected
asymptomatic patients receiving either monotherapy with AZT, didanosine ( ddI ), or
stavudine ( d4T ), or combination antiretroviral therapy with AZT / ddI or AZT / zalcitabine
( ddC ).
Source: Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Treatment Study to assess of safety and efficiency of T cells receptor (TCR) alfa beta
depleted graft for hematopoietic stem cell transplantation (HSCT) from haploidentical and
unrelated donors in patients with primary immunodeficiency diseases
We hypothesize that there is a statistically significant difference in miRNA profiling and
expression of subjects with asthma upon its exacerbation compared to patient's baseline
level or following effective treatment of an exacerbation of asthma. Therefore, plasma miRNA
profiling may provide noninvasive, highly specific and sensitive biomarkers for asthma
exacerbation's detection and treatment follow-up.
Source: The Center for Rheumatic Disease, Allergy, & Immunology
- This is the first study, that we are aware of, that will evaluate the efficacy of IgIV
in patients with IgG subclass deficiency.
- Will provide data for further collaboration in extending study to involve other
immunological centers in the United States to study patients with similar disease.
Source: Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences
The primary purpose of this experimental therapy is to treat, with the aid of
bacteriophages, patients with non-healing postoperative wounds or bone, upper respiratory
tract, genital or urinary tract infections in whom extensive antibiotic therapy failed or
the use of the targeted drug is contraindicated.
Source: Sanjay Gandhi Postgraduate Institute of Medical Sciences
Raynaud's phenomenon (RP) associated with scleroderma is a difficult problem to treat. Many
patients develop ischemic digital ulcers due to severe RP that causes considerable morbidity
and adversely affects the quality of life. In an earlier study, we have observed marked
improvement in RP attacks and rapid healing of digital ulcers following therapy with
phosphodiesterase V inhibitor, Tadalafil. In the present multicentric study we aim to study
the efficacy ... Read More