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Clinical Trials: Cardiothoracic Surgery

Source: Levanger Hospital
The investigators aim to study the feasibility and reliability of pocket-size diagnostic ultrasound examinations performed by nurses of postoperative patients who have underwent cardiothoracic surgery in a cardiac unit. Read More
Last Updated: 12 Jan 2014
Source: Merck Sharp & Dohme Corp.
This study will assess the efficacy of a single dose of V710 vaccine to prevent serious Staphylococcus aureus infections following elective cardiothoracic surgery. The study will also evaluate the immune response and general safety of the V710 vaccine. Read More
Last Updated: 30 Sep 2015
Source: The Hospital for Sick Children
The objective is to the amount of protein infants require after cardiopulmonary bypass surgery. Read More
Last Updated: 15 Aug 2013
Source: Hartford Hospital
The purpose of this study is to see if ascorbic acid (Vitamin-C) therapy will reduce inflammation following heart surgery. Read More
Last Updated: 02 Jan 2012
Source: University of California, Los Angeles
The thymus is known to be the site of T cell development in humans. Due to its location in the chest in front of the heart, incidental thymecomy is commonly performed during cardiothoracic surgery, especially in infants and children, so that surgeons may gain access to the surgical field. This practice has been considered safe because it was thought that the thymus is inactive after birth. However, recent data using newly developed techniques has ... Read More
Last Updated: 22 Aug 2016
Source: Creighton University
This study will compare the effects of 20 mg of atorvastatin to 80 mg of atorvastatin for the prevention of atrial fibrillation after cardiothoracic surgery. The study hypothesis is that 80 mg of atorvastatin will be more effective at preventing atrial fibrillation compared to 20 mg. Read More
Last Updated: 14 Jun 2016
Source: Baxter Healthcare Corporation
The study is to evaluate the effectiveness and safety of CELSTAT vs active control. Read More
Last Updated: 20 Oct 2016
Source: Ohio State University
In this study we will determine the proper method for transitioning patients from a continuous insulin infusion to periodic injections of a newer long-acting insulin called detemir (Levemir). Read More
Last Updated: 29 Aug 2011
Source: Medical University of Vienna
This is a randomized, prospective European Multicenter Study comparing complete arterial revascularization of the coronary arteries using arterial graft material exclusively and “conventional” coronary artery bypass surgery using the left internal thoracic artery as graft to the left anterior descending artery (LAD) and vein grafts to other vessels to be bypassed. Read More
Last Updated: 11 Oct 2006
Source: Allon Therapeutics
The primary objective is to compare mild cognitive impairment in the AL-208 group with the placebo group at 14 + - 3 days after CABG surgery Read More
Last Updated: 17 Oct 2012
Source: Children's Hospitals and Clinics of Minnesota
All pediatric patients who undergo cardiac surgery require analgesic medications for postoperative pain control and many require sedation to facilitate comfort with cares. Parasternal infiltration of local anesthetic for nerve blocks is a simple option to postoperative analgesia. The investigators hypothesize that Bupivacaine, a parasternal nerve block administered in pediatric patients undergoing cardiac surgery will reduce the requirement of Opioids and ... Read More
Last Updated: 20 Jun 2016
Source: Advocate Health Care
The investigators hypothesize that intermittent bolus doses of morphine and midazolam can provide the same pain control after pediatric cardiothoracic surgery as bolus doses plus infusions while using smaller total doses of both medications. The investigators will randomize patients to receive either morphine/midazolam as needed intermittently or morphine/midazolam drips plus intermittent doses to be received as needed. Pain scores will be recorded and ... Read More
Last Updated: 17 Sep 2016
Source: Institut für Pharmakologie und Präventive Medizin
This is an international multi-center, prospective, observational registry with consecutive patient enrollment intended to determine outcome Parameters within 30 days after transaortic transcatheter aortic valve replacement. Read More
Last Updated: 09 Aug 2016
Source: University of Aarhus
In this study we will focus on the postoperative recovery. A successful postoperative recovery should bring the patient to at least to the pre-surgical level. This can probably be achieved by a multimodal approach where at least postoperative pain and PONV are managed. The surgical injury results in immobilisation which again can result in impaired cardiac, respiratory and musculoskeletal system. Pain relief is a prerequisite for mobilisation and an early ... Read More
Last Updated: 11 Feb 2009
Source: Rigshospitalet, Denmark
The purpose of the study is to reduce the incidence of postoperative constipation by systematic nurse assessment, interventions and evaluation, in the first month after thoracic surgery. Read More
Last Updated: 26 Jun 2008
Source: Assiut University
The lung is at risk for ischemic insults during total cardiopulmonary bypass because lung perfusion is maintained solely by the bronchial arterial system Read More
Last Updated: 16 Jan 2017
Source: Sahlgrenska University Hospital, Sweden
The study hypothesis is that prophylactic fibrinogen infusion reduces postoperative bleeding and transfusion requirements after coronary artery bypass surgery (CABG) in patients with endogenous fibrinogen levels in the lower normal range. 60 patients will be included in a prospective, randomized double-blind placebo-controlled single center study. Read More
Last Updated: 18 May 2015
Source: M.D. Anderson Cancer Center
The goal of this research study is to develop a method of rating videos of CAB procedures that will produce a reliable assessment of a cardiothoracic surgical trainee's technical proficiency. In addition, researchers also want to learn if using a video manual to train raters can help improve rater reliability. Read More
Last Updated: 26 Jan 2017
Source: Ullevaal University Hospital
Hypothesis: Treatment with levosimendan will preserve myocardial function and hemodynamics after cardiac surgery and lead to reduced stay at intensive care unit Read More
Last Updated: 31 Oct 2010
Source: Los Angeles Biomedical Research Institute
This investigation is a prospective, open-label pharmacokinetic study of daptomycin prophylaxis in patients undergoing coronary artery bypass graft surgery without valvular replacement. Read More
Last Updated: 18 Jul 2016
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