The investigators aim to study the feasibility and reliability of pocket-size diagnostic
ultrasound examinations performed by nurses of postoperative patients who have underwent
cardiothoracic surgery in a cardiac unit.
This study will assess the efficacy of a single dose of V710 vaccine to prevent serious
Staphylococcus aureus infections following elective cardiothoracic surgery. The study will
also evaluate the immune response and general safety of the V710 vaccine.
The thymus is known to be the site of T cell development in humans. Due to its location in
the chest in front of the heart, incidental thymecomy is commonly performed during
cardiothoracic surgery, especially in infants and children, so that surgeons may gain access
to the surgical field. This practice has been considered safe because it was thought that
the thymus is inactive after birth. However, recent data using newly developed techniques
has ... Read More
This study will compare the effects of 20 mg of atorvastatin to 80 mg of atorvastatin for
the prevention of atrial fibrillation after cardiothoracic surgery. The study hypothesis is
that 80 mg of atorvastatin will be more effective at preventing atrial fibrillation compared
to 20 mg.
In this study we will determine the proper method for transitioning patients from a
continuous insulin infusion to periodic injections of a newer long-acting insulin called
This is a randomized, prospective European Multicenter Study comparing complete arterial
revascularization of the coronary arteries using arterial graft material exclusively and
“conventional” coronary artery bypass surgery using the left internal thoracic artery as
graft to the left anterior descending artery (LAD) and vein grafts to other vessels to be
Source: Children's Hospitals and Clinics of Minnesota
All pediatric patients who undergo cardiac surgery require analgesic medications for
postoperative pain control and many require sedation to facilitate comfort with cares.
Parasternal infiltration of local anesthetic for nerve blocks is a simple option to
postoperative analgesia. The investigators hypothesize that Bupivacaine, a parasternal nerve
block administered in pediatric patients undergoing cardiac surgery will reduce the
requirement of Opioids and ... Read More
The investigators hypothesize that intermittent bolus doses of morphine and midazolam can
provide the same pain control after pediatric cardiothoracic surgery as bolus doses plus
infusions while using smaller total doses of both medications.
The investigators will randomize patients to receive either morphine/midazolam as needed
intermittently or morphine/midazolam drips plus intermittent doses to be received as needed.
Pain scores will be recorded and ... Read More
Source: Institut für Pharmakologie und Präventive Medizin
This is an international multi-center, prospective, observational registry with consecutive
patient enrollment intended to determine outcome Parameters within 30 days after transaortic
transcatheter aortic valve replacement.
In this study we will focus on the postoperative recovery. A successful postoperative
recovery should bring the patient to at least to the pre-surgical level. This can probably
be achieved by a multimodal approach where at least postoperative pain and PONV are managed.
The surgical injury results in immobilisation which again can result in impaired cardiac,
respiratory and musculoskeletal system. Pain relief is a prerequisite for mobilisation and
an early ... Read More
The study hypothesis is that prophylactic fibrinogen infusion reduces postoperative bleeding
and transfusion requirements after coronary artery bypass surgery (CABG) in patients with
endogenous fibrinogen levels in the lower normal range. 60 patients will be included in a
prospective, randomized double-blind placebo-controlled single center study.
The goal of this research study is to develop a method of rating videos of CAB procedures
that will produce a reliable assessment of a cardiothoracic surgical trainee's technical
proficiency. In addition, researchers also want to learn if using a video manual to train
raters can help improve rater reliability.