RATIONALE: Endoscopic breast surgery (EBS) is a less invasive type of surgery for breast
cancer and may have fewer side effects and improve recovery. PURPOSE: This clinical trial
studies endoscopic breast surgery in treating patients with breast cancer.
RATIONALE: A questionnaire that evaluates a patient's expectations about breast
reconstruction surgery may help doctors improve patient education before surgery and
increase patient satisfaction after surgery.
PURPOSE: This clinical trial is developing a questionnaire to evaluate patient expectations
for breast reconstruction in women with breast cancer or other conditions.
This paper will present a specific tool for evaluation of cosmetic results after breast
conserving surgery (BCS) and secondary breast reconstruction with free DIEP-flap.
Introduction of a breast score system using digital photography seems to be a reliable tool
for estimation of cosmetic results after breast surgery. The method has been employed on a
specific group of 346 consecutive patients operated for breast cancer with breast conserving
surgery. For the ... Read More
Aromasin® (Exemestane) was approved in China for adjuvant treatment of postmenopausal women
with estrogen receptor (ER) positive early invasive breast cancer who have received 2-3
years of tamoxifen & are switched to Aromasin® for completion of a total of 5 consecutive
years of adjuvant hormonal therapy by State Food and Drug Administration (SFDA) with
clinical trial waive. While Aromasin® has been used in China for adjuvant therapy of breast
cancer since ... Read More
RATIONALE: Breast-conserving surgery is a less invasive type of surgery for breast cancer
and may have fewer side effects and improve recovery. Radiation therapy uses high-energy
x-rays to kill tumor cells. Giving radiation therapy after surgery may kill any tumor cells
that remain after surgery.
PURPOSE: This phase II clinical trial is studying how well breast-conserving surgery
followed by radiation therapy works in treating patients with stage I or stage ... Read More
A randomized trial evaluating resection of the primary breast tumor in women presenting with
de novo stage IV breast cancer with bone metastasis only. Previous reports of carefully
selected patients presenting with stage IV breast cancer suggest that surgery on the primary
tumor may result in improved survival, but this remains unproven. The early results of our
ongoing trial MF07-01 trial (a phase III randomized controlled trial of breast cancer women
with ... Read More
Rationale: Like in primary breast cancer, prognosis in recurrent breast cancer is correlated
with regional lymph node status. Therefore, axillary staging may be warranted in patients
with recurrent disease and intact axillary nodes, although this has not been described in
guidelines yet. The lymphatic drainage pathways in the breast and/or axilla could have been
changed due to prior surgery and/or radiotherapy. These aberrant drainage pathways could be
... Read More
The hypothesis to be addressed in this randomized phase III trial is that 4 months of
letrozole may be superior to surgery as primary therapy for early stage hormone receptor
positive breast cancer in postmenopausal women, provided that these patients will receive
definitive and radical surgery and adjuvant therapies as otherwise indicated at the
completion of preoperative letrozole.
The goal of the study is measure breast sensations after breast surgery. The results of this
study will help surgeons better understand breast sensations and may improve the way surgery
Breast tissue and the areas surrounding the breast contain many small to medium-sized
nerves. During surgery on the breast, these nerves can be inadvertently cut or damaged.
Chemotherapy and radiotherapy after surgery worsen the injury experienced by these nerves.
These nerves eventually become abnormal and provide pain signals to the brain well beyond
the healing period after surgery. Patients with these abnormal nerves suffer from chronic
pain in the ... Read More
Whether the patients with low grade ductal carcinoma in situ breast cancer should accept
radiationtherapy is uncertain.Radiation therapy uses high-energy x-rays to damage tumor
cells. Giving radiation during surgery followed by external-beam radiation to the entire
breast may kill more tumor cells.The clinical trial is conducting to find out the
effectiveness of radiation therapy during surgery in treating women who have undergone
breast-conversing surgery ... Read More
RATIONALE: Diagnostic procedures, such as dynamic contrast-enhanced magnetic resonance
imaging(DCE-MRI), magnetic resonance spectroscopy (MRS), and tissue proteomics, may help
doctors find and diagnose breast cancer and plan the best treatment.
PURPOSE: This clinical trial is studying MRI and MRS with or without tissue proteomics
analysis to see how well they work in evaluating healthy women and women who are undergoing
surgery for breast cancer.
The purpose of the study is to collect data regarding the aesthetic outcomes of patients who
had breast reduction surgery and /or mastopexy in terms such as scaring, patient
satisfaction, breast ptosis assessment including taking photographs and filling
RATIONALE: Certain psychological and social factors may increase the risk of developing
chronic pain after surgery. Evaluating these factors over time in patients who have
undergone surgery for breast cancer may help doctors plan treatment and improve patients'
quality of life.
PURPOSE: This clinical trial is studying the psychological and social factors that may
increase the risk of developing chronic pain after surgery in women with breast cancer .
The study was designed to evaluate the feasibility and safety of hypofractionated
whole-breast irradiation with simultaneously integrated boost for early-stage breast cancer
after breast conserving surgery in Chinese population.
RATIONALE: Gathering information about strength and range of motion over time from women
undergoing surgery for breast cancer may help doctors learn more about recovery from surgery
and on-going care.
PURPOSE: This clinical trial is collecting information about strength and range of motion
over time from women undergoing surgery for breast cancer.
This is a pilot, non-randomized, single institution, observational study investigating the
effect of dramatic weight loss secondary to bariatric surgery on biomarkers of breast cancer
in tissue and blood as well as on imaging in women at elevated risk for breast cancer.
Twelve months after bariatric surgery, 50% of excess weight is generally expected. Eligible
women at elevated risk for breast cancer who are already planning to undergo bariatric
surgery will ... Read More
This phase II trial studies how well giving eribulin mesylate and carboplatin together
before surgery works in treating patients with stage I-III triple-negative breast cancer.
Drugs used in chemotherapy, such as eribulin mesylate and carboplatin, work in different
ways to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Giving chemotherapy before surgery may make the tumor smaller and reduce the
amount of normal ... Read More