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Clinical Trials: Anesthetics

Source: Nanjing Medical University
Previous studies on animals suggest that inhalational anesthetics can reduce vascular tension in vitro resulting in vasodilation and decrease in blood pressure. This role for inhalational anesthetics has essential clinical implications such as the condition of sepsis or septic shock or other shock-associated states during which the blood vessel constricts strongly and leads to circulation dysfunction. The vasodilation property of these anesthetics including ... Read More
Last Updated: 21 Dec 2009
Source: Kangbuk Samsung Hospital
The purpose of this clinical trial is to compare analgesic effect of sevoflurane and desflurane at equal minimum alveolar concentrations using surgical pleth index. Read More
Last Updated: 08 Jul 2016
Source: Nanjing Medical University
It is common for obstetric anesthesia using opioid supplement to local anesthetics for epidural labor pain control. Given the low doses of these epidural drugs, we never doubt the necessity of the supplement of opioid to lacal anesthetics during this process based on the concept that opioid addition can enhance and prolong the analgesic effect of local anesthetics. However, we unavoidably encounter many opioid-associated side effects during the labor ... Read More
Last Updated: 31 Jan 2014
Source: University of Virginia
Epidural local anesthetics are the gold standard for shortening duration of bowel dysfunction after bowel surgery. Previous studies suggest that their effect may be in part a result of actions of the local anesthetic outside the epidural space. If local anesthetics could be administered intravenously instead, this might be a safer, easier and less expensive approach. Therefore, this trial will compare the effect on bowel function recovery of intravenous ... Read More
Last Updated: 22 Jan 2008
Source: UPECLIN HC FM Botucatu Unesp
The purpose of this study is to evaluate if the anesthetics propofol and isoflurane can damage DNA, induce apoptosis, change expression of genes related to apoptosis and DNA repair and change cytokines profile in patients submitted to elective surgery. Read More
Last Updated: 04 Jan 2010
Source: University of Campinas, Brazil
This blinded cross-over study aim to evaluate the efficacy of liposome-encapsulated ropivacaine formulation for dental anesthesia. Read More
Last Updated: 01 Mar 2011
Source: Chonnam National University Hospital
The purpose of this study is to evaluate the analgesic efficacy of perineural fentanyl combined with local anesthetics in the post operative pain control with continuous femoral nerve block after total knee arthroplasty. Read More
Last Updated: 24 Jul 2016
Source: Okayama University
To evaluate an analgesic effect without basal administration of local anesthetics for patient-controlled femoral nerve block (with sciatic nerve block) after total knee arthroplasty. Read More
Last Updated: 19 Jul 2011
Source: University of Michigan
The efficacy of the topical anesthetics will be determined by how much pain the patient felt (using a Heft-Parker pain analog scale) upon needle penetration. Read More
Last Updated: 11 Jun 2016
Source: Technische Universität München
The aim of the present study is to investigate and quantify the influence of commonly used anesthetics on auditory and pain evoked potentials. Read More
Last Updated: 23 Sep 2007
Source: Medical University of South Carolina
Comparison of propofol and sevoflurane as a primary anesthetic for cardiac ablation of atrial fibrillation Read More
Last Updated: 10 Nov 2016
Source: Beth Israel Deaconess Medical Center
The purpose of this study is to investigate whether the use of inhaled anesthetics, compared to intravenous anesthetics, can effect the amount of lung inflammation and postoperative respiratory complications seen after cardiac surgery. Read More
Last Updated: 26 Sep 2016
Source: Bassett Healthcare
To find out if the administration of the local pharyngeal anesthetic, lidocaine, in conjunction with Propofol during elective Esophagogastroduodenoscopy (EGD) is useful, safe and impacts the time of discharge of patient compared to placebo. Read More
Last Updated: 05 Jan 2017
Source: First Hospital of China Medical University
The investigators designed a prospective, randomized, placebo-controlled study to determine whether thoracic epidural anesthesia(TEA) with different local anesthetics has different influences on the propofol dose during induction. Read More
Last Updated: 19 Apr 2014
Source: Kolding Sygehus
To extend the duration of peripheral nerve blockade after major foot and ankle surgery the investigators randomize the postoperative treatment with either perineurial sciatic nerve blocks with 0.5% Bupivacaine-Epinephrine with or without Dexamethasone. Read More
Last Updated: 21 Sep 2016
Source: Seoul National University Hospital
The purpose of this study is to compare the frequency of hypotension between hyperbaric anesthetics and isobaric anesthetics during cesarean section and determine whether continuous infusion of phenylephrine is effective in mothers who received hyperbaric anesthetics. Read More
Last Updated: 03 Jul 2016
Source: University of Zurich
This study aims to evaluate the attenuation of ischemic-reperfusion injury in the liver after sevoflurane preconditioning. In the presence of sevoflurane, an attenuation of liver injury is hypothesized (diminished increase of liver enzymes, reduced production of inflammatory mediators). Read More
Last Updated: 13 Sep 2010
Source: Bausch & Lomb Incorporated
The purpose of this study is to evaluate Vitrase as an adjuvant to increase absorption and dispersion of other injected anesthetics Read More
Last Updated: 14 Mar 2013
Source: Nanjing Medical University
Cognitive disorders in patients underwent general anesthesia are discussed for decades, but whether there were precise relationship between general anesthesia and dysgnosia is yet to be guaranteed. Although controversial data reported from experimental studies in animals, the investigators still proposed that general anesthetics could impair the normally organized system of the central nervous system, which finally displayed a dysfunction of cognition after ... Read More
Last Updated: 10 Jan 2014
Source: Yonsei University
Living-donor kidney transplantation has been considered as the best treatment for patients with end-stage renal disease (ESRD). Kidney donation from living donors has been performed widely under their noble humanity and a belief that donation would not harm the donor. Although the overall evidences proposed that living kidney donor have medical outcomes similar to those in general population, several reports have demonstrated the potential risks for ... Read More
Last Updated: 25 Jan 2015
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