Previous studies on animals suggest that inhalational anesthetics can reduce vascular
tension in vitro resulting in vasodilation and decrease in blood pressure. This role for
inhalational anesthetics has essential clinical implications such as the condition of sepsis
or septic shock or other shock-associated states during which the blood vessel constricts
strongly and leads to circulation dysfunction. The vasodilation property of these
anesthetics including ... Read More
It is common for obstetric anesthesia using opioid supplement to local anesthetics for
epidural labor pain control. Given the low doses of these epidural drugs, we never doubt the
necessity of the supplement of opioid to lacal anesthetics during this process based on the
concept that opioid addition can enhance and prolong the analgesic effect of local
anesthetics. However, we unavoidably encounter many opioid-associated side effects during
the labor ... Read More
Epidural local anesthetics are the gold standard for shortening duration of bowel
dysfunction after bowel surgery. Previous studies suggest that their effect may be in part a
result of actions of the local anesthetic outside the epidural space. If local anesthetics
could be administered intravenously instead, this might be a safer, easier and less
expensive approach. Therefore, this trial will compare the effect on bowel function recovery
of intravenous ... Read More
The purpose of this study is to evaluate if the anesthetics propofol and isoflurane can
damage DNA, induce apoptosis, change expression of genes related to apoptosis and DNA repair
and change cytokines profile in patients submitted to elective surgery.
The purpose of this study is to evaluate the analgesic efficacy of perineural fentanyl
combined with local anesthetics in the post operative pain control with continuous femoral
nerve block after total knee arthroplasty.
The purpose of this study is to investigate whether the use of inhaled anesthetics, compared
to intravenous anesthetics, can effect the amount of lung inflammation and postoperative
respiratory complications seen after cardiac surgery.
To find out if the administration of the local pharyngeal anesthetic, lidocaine, in
conjunction with Propofol during elective Esophagogastroduodenoscopy (EGD) is useful, safe
and impacts the time of discharge of patient compared to placebo.
Source: First Hospital of China Medical University
The investigators designed a prospective, randomized, placebo-controlled study to determine
whether thoracic epidural anesthesia(TEA) with different local anesthetics has different
influences on the propofol dose during induction.
To extend the duration of peripheral nerve blockade after major foot and ankle surgery the
investigators randomize the postoperative treatment with either perineurial sciatic nerve
blocks with 0.5% Bupivacaine-Epinephrine with or without Dexamethasone.
The purpose of this study is to compare the frequency of hypotension between hyperbaric
anesthetics and isobaric anesthetics during cesarean section and determine whether
continuous infusion of phenylephrine is effective in mothers who received hyperbaric
This study aims to evaluate the attenuation of ischemic-reperfusion injury in the liver
after sevoflurane preconditioning. In the presence of sevoflurane, an attenuation of liver
injury is hypothesized (diminished increase of liver enzymes, reduced production of
Cognitive disorders in patients underwent general anesthesia are discussed for decades, but
whether there were precise relationship between general anesthesia and dysgnosia is yet to
be guaranteed. Although controversial data reported from experimental studies in animals,
the investigators still proposed that general anesthetics could impair the normally
organized system of the central nervous system, which finally displayed a dysfunction of
cognition after ... Read More
Living-donor kidney transplantation has been considered as the best treatment for patients
with end-stage renal disease (ESRD). Kidney donation from living donors has been performed
widely under their noble humanity and a belief that donation would not harm the donor.
Although the overall evidences proposed that living kidney donor have medical outcomes
similar to those in general population, several reports have demonstrated the potential
risks for ... Read More