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Source: University of Copenhagen
Background Statins are cholesterol lowering drugs that are prescribed to lower the risk of cardio-vascular diseases. The use of statins has increased markedly and it is now one of the most prescribed drugs in the world. 600,000 people in Denmark are taking statins on a daily basis, 40 % of these are taking the medication without having any other risk factors for cardio-vascular diseases than elevated blood-cholesterol i.e. they are in primary prevention. ... Read More
Last Updated: 02 Jan 2017
Source: Centre Hospitalier Universitaire Vaudois
The important role played by the GI tract microflora on the metabolic health of an individual are increasingly recognized. In this respect, the initial studies of Metchinkoff that suggested a role of fermented food (specifically yoghourts ) to modulate the gut microflora have evolved into the concept of "probiotics". Probiotics are living microorganisms that bring a benefit to the host when administered in sufficient quantity (WHO/FAO, 2001). Here the ... Read More
Last Updated: 19 Aug 2015
Source: University of Magdeburg
Statement: Patients with Chronic kidney disease (CKD) with an estimated glomerular filtration rate (eGFR) under 60 ml/min using the MDRD-6 (Modification of Diet in Renal Disease) formula and/or CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) formula should undergo nephrological and urological care (diagnosis and treatment) to prevent chronic kidney failure. This is recommended by the National Kidney Foundation Kidney Disease Outcomes ... Read More
Last Updated: 27 Aug 2014
Source: Pfizer
Study B7451005 is a Phase 2 study which will assess the efficacy and safety of PF-04965842 in patients with moderate to severe psoriasis. The study will include three PF-04965842 groups (200 mg daily, 400 mg daily and 200 mg twice daily) and a placebo group. The treatment period will be 4 weeks in duration and will be followed up by a 4 week follow up period. Read More
Last Updated: 10 Aug 2016
Source: Danisco Sweeteners Oy
To determine if Bifidobacterium lactis HN109 improves transit time and gastrointestinal symptoms in adults with constipation. Read More
Last Updated: 05 May 2015
Source: Asklepieion Voulas General Hospital
Combination of continuous femoral block with parEcoxib vs placebo. Investigation of morphine consumption, opioid sparing effects, VAS pain scores, haemodynamics, Anxierty scores, transfusion requirements , Range of motion and rehabilitation parameters between two groups Read More
Last Updated: 06 Jul 2014
Source: Meir Medical Center
The investigators are studying the difference between the history taken from parents prior to their child's anesthesia to information gleaned routinely from a patient information system called Ofek. Read More
Last Updated: 26 Apr 2015
Source: M.D. Anderson Cancer Center
The goal of this clinical research study is to compare the effectiveness of liposomal amphotericin B given three times per week , versus liposomal amphotericin B given once per week, versus oral voriconazole in the prevention of fungal infections in patients with acute myeloid leukemia (AML) or myelodysplastic syndromes MDS who are receiving chemotherapy. The safety of these treatments will also be studied and compared. Read More
Last Updated: 31 Jul 2012
Source: Princess Alexandra Hospital, Brisbane, Australia
The purpose of this study is to determine whether the incidence of recurrent life threatening ventricular arrhythmias in patients with an implanted cardiac defibrillator (ICD) can be reduced if a surgical left stellate ganglionectomy is performed. Read More
Last Updated: 28 Mar 2016
Source: University of Rochester
This randomized clinical trial studies standardized geriatric assessment (GA) or usual care in improving communication and quality of life in older patients with advanced solid tumors or lymphoma and their caregivers. A GA measures the issues important to older patients, including function, psychological status, cognitive abilities, social support, and the impact of medical problems on quality of life. A GA may improve communication between patients and ... Read More
Last Updated: 03 Jan 2017
Source: Shiraz University of Medical Sciences
new glidoscope was tested on 401 patients Read More
Last Updated: 19 Mar 2014
Source: Qilu Hospital
Objective: To evaluate whether long-term oral N-acetylcysteine as an expectorant drug can reduce the frequency of acute exacerbations of patients with non-cystic fibrosis bronchiectasis and improve their quality of life. Methods: Patients with non-cystic fibrosis bronchiectasis will be randomly assigned to the observer group (participants receive 600 mg of oral N-acetylcysteine BID for 12 months) or the control group (participants receive oral tablet BID ... Read More
Last Updated: 22 Jul 2016
Source: University of Iowa
Arrhythmias remain a major health problem, causing at least 250,000 deaths annually in the United States. Pharmacological treatments often do more harm than good, and device therapies are limited by high cost and effects on quality of life. Ion channel mutations cause rare inherited arrhythmopathies, but account for only a small fraction of patients with life- threatening arrhythmias and sudden death. Most arrhythmias occur during myocardial ischemia, ... Read More
Last Updated: 21 Jan 2014
Source: Aarhus University Hospital
To investigate the reported health benefits (lipid profile, inflammatory factors, cardiovascular status and bone density) of a novel, phytoestrogen rich, Red Clover treatment on women suffering from both menopause related primary (hot flushes, night sweats, sleep disturbance and weight gain) and secondary (osteoporosis, cardiovascular and changes in lipid metabolism) symptoms. Read More
Last Updated: 04 Feb 2015
Source: Ospedali Riuniti Ancona
The objective of this randomized study is to compare the effect of two controlled chest tube protocols on the duration of air leak and fluid drainage following pulmonary lobectomy or segmentectomy by using an electronic regulated chest drainage system (Thopaz). Previous studies have suggested that the amount of negative pressure used at the level of the chest drainage device may affect the duration of air leak, but the results have been inconsistent, however ... Read More
Last Updated: 27 Mar 2016
Source: Baylor College of Medicine
Sturge Weber Syndrome (SWS) is a rare disease that affects the patient's brain and causes benign (non-cancerous) tumors to grow in the brain. One of the symptoms of SWS is epilepsy. People with epilepsy have seizures. Some patients may also have eye problems and a red mark on their facial skin. This study is being done to find out if the study drug, everolimus, is safe and has helpful effects in patients with SWS who have seizures and are not responding to ... Read More
Last Updated: 03 May 2016
Source: ZhuHai Cardionovum Medical Device Co., Ltd.
To evaluate the safety and efficacy of the paclitaxel-eluting peripheral balloon dilatation catheter (LEGFLOW) compare to the PTA catheter (AMPHIRION DEEP).in treatment of inferior genicular artery stenosis or occlusion. Read More
Last Updated: 09 Nov 2016
Source: University of Göttingen
Partially defective dental restorations might either be treated by complete replacement or by repair of the affected region. Repair restorations are a scientifically proven approach to manage failed restorations, but probably unknown to most patients. Results from this study and findings on the predictors of patients' therapy decisions might improve future patient information documents. Read More
Last Updated: 21 Jan 2017
Source: University of Regensburg
The goal of this study is to increase the efficiency of exposure in virtual reality (VR). Based on the EMDR research the investigators would like to show that the implementation of eye movements during the VR exposure results in a faster physiological relaxation response among probands with spider phobia, which has a positive effect on the subjective and behavioral efficacy of the VR exposure. Read More
Last Updated: 20 Nov 2016
Source: Sunovion
A study to evaluate the safety and tolerability of SEP363856 in subjects with Parkinson's Disease Psychosis Read More
Last Updated: 09 Jan 2017
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