The proportion of the elderly population has increased rapidly worldwide. Frailty is a
common geriatric syndrome. Comprehensive dietary management strategy may have beneficial
effects on frailty prevention and reversal. We compared the effects between micronutrients
and/or protein supplement, and balanced diet on frailty status in elderly individuals who
were at either pre-frail or frail stage. A total of 37 subjects completed a 3-month
paralleled, ... Read More
The goal of this study is to assess whether children 12-18 months of age who are exposed to
multiple large-scale vitamin A programs, and who are likely to have vitamin A intakes above
the tolerable upper intake level (UL), have higher total body vitamin A stores and
biomarkers of excessive vitamin A status, compared to children 12-18 months of age who have
adequate vitamin A intake.
Teduglutide is approved for treatment of adults with short bowel syndrome (SBS). The purpose
of this study is to evaluate the safety and efficacy of teduglutide in children up to the
age of 17 with SBS who are dependent on parenteral support. Subjects may choose whether to
receive the study drug or to participate in a standard-of-care arm. All participants who
complete the study may be eligible to receive the study drug in a long-term extension study.
Source: USDA, Western Human Nutrition Research Center
The purpose of this study is to determine if consumption of meals containing carbohydrates
with different glycemic index (a high glycemic index meal and a low glycemic index meal)have
different effects on energy expenditure, type of metabolic fuels used for energy, blood
lipids and lipoproteins, and sensations of hunger, fullness, and the hormones related to
Source: Clinical Nutrition Research Centre, Singapore
The primary hypothesis of this study is that consumption of capsinoids increases brown
adipose tissue activity, detectable by infrared thermal imaging.
The secondary hypothesis is that consumption of capsinoids can affect an individual's
The present study aims to develop a technique based on a single dose of a calcium isotope,
which enables to determine the effect of a nutritional intervention on bone calcium
metabolism. For this purpose nutritional interventions with calcium, vitamin D and vitamin K
will be applied in postmenopausal women. Treatment effects will be determined by the urinary
excretion of the calcium isotope and related to classical bone markers.
A natural form of vitamin E called tocotrienol (TCT) has blood thinning and cholesterol
lowering properties, both of which may benefit stroke survivors. This study is being
conducted to determine the blood thinning and cholesterol lowering properties of TCT in
stroke or TIA (transient ischemic attack, which is also referred to as a "mini-stroke")
survivors that are receiving the standard treatment for prevention of recurrent stroke.
Study Hypothesis: Oral ... Read More
Source: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
The purpose of this study is to determine whether a nutrition and physical activity
education program for families of overweight or obese adolescents with Down syndrome is more
effective when behavioral lifestyle change strategies are added.
The epidermal barrier efficacy is determined by the physicochemical properties of the
epidermal lipid matrix, among which ω-6 essential fatty acids (EFAs) play a key role.
Inversely, the ω-3 EFAs are not found in the epidermis. For patients receiving
lipid-containing parenteral nutrition (LCPN), the improvement of the epidermal barrier
through the infusion of most appropriate intravenous fat emulsions (IVFE) could have many
applications in clinical ... Read More
Source: USDA Beltsville Human Nutrition Research Center
The objective of this study is to evaluate the effects of different quantities of lean beef
(0.5, 2.5, 5.5 oz/day) on lipids, lipoproteins, and vascular health endpoints in the context
of a modified Mediterranean dietary pattern that is representative of foods typically
consumed in the United States.
Many patients in the hospital who are malnourished or not eating received intravenous
feeding or total parenteral nutrition (TPN). Despite improving nutrition, TPN may increase
the risk of infections and hospital complications. We do not know why TPN increases hospital
complications, but it may be caused by the high sugar or fat content in TPN solutions. The
investigators believe that the high sugar and high fat content can limit the ability to
fight ... Read More
Source: National Nutrition and Food Technology Institute
To study the effects of Flaxseed supplement on lipid profile, liver enzymes, inflammatory
factors and hepatic fibrosis in patients with Nonalcoholic Steatohepatitis (NASH), 50
patients who referred to Gastrointestinal (GI) clinic with steatosis grade 2 and 3 will be
randomly allocated to receive placebos or 30 grams Flaxseed powder for 12 weeks; both groups
will be advised to adherence the investigators' diet and exercise program too. At the first
and the ... Read More
Omitting evaluation of gastric residual contents prior to feeding very premature infants
will increase the feeding intake at 2 weeks, and total caloric intake and growth by 3 weeks,
as well as decrease the time required for parenteral nutrition.
Study objectives are to verify the loss of lean mass during a hospital stay in a group of
older patients; to evaluate the effects of consuming a high-calorie complete and balanced
oral nutritional supplement; to collect post-discharge information.
Source: National Institute of Nutrition and Seafood Research, Norway
NSAIDS are associated with adverse GI effects and COX-2 inhibitors have cardiovascular risk.
Long-term oral supplementation with fish oil reduce e.g. joint pain in rheumatoid arthritis
(R.A) patients, with reduced need for NSAIDS, in addition to being cardioprotective. The aim
is to investigate if 4 month supplementation of 15 ml/day of whale blubber oil compared with
cod liver oil reduce the intensity of joint pain in patients with R.A (primary outcome).
... Read More
The purpose of this study is to determine whether fluid or glucose administration before hip
replacement surgery minimizes postoperative muscle breakdown (catabolism), fatigue and
disturbances in carbohydrate metabolism.
This study tests the hypothesis that initial trophic enteral feedings will increase the time
alive and free of mechanical ventilation as compared to initial goal enteral feedings in
patients who are mechanically ventilated.