The purpose of this study is to determine whether very low birth weight infants (less than
or equal to 1250g or about 2 3/4 pounds) born prematurely fed a diet of only human milk and
human milk-derived nutrition have better health outcomes than babies fed at least some
formula (made from cow's milk)or formula-derived nutrition.
In critically ill patients, a strategy aimed at an early delivery of full caloric support,
with a combination of Enteral Nutrition (EN) and Parenteral Nutrition (PN) (in conditions
preventing hyperglycemia and overfeeding), results in shorter ICU and hospital stay and less
morbidity as compared to a strategy using only EN.
While fish-oil lipid emulsions have shown a benefit to the treatment of parenteral nutrition
(PN)-associated cholestasis, the dose is limited to 1 g/kg/day. Similarly, in early
PN-associated cholestasis the dose of soy-based lipid is limited to 1 g/kg/day. Often the
calories that are lost from this relative decreased dose of lipids can be provided by
adjusting the dextrose content of the PN solution and providing a higher glucose infusion
rate. In some ... Read More
Non-alcoholic fatty liver disease (NAFLD) is considered as the hepatic manifestation of the
metabolic syndrome. NAFLD is a pathologic condition which involves both hepatic steatosis
and non alcoholic steatohepatitis (NASH), as the result of fat accumulation in the liver
(liver fat >5-10% of liver weight), not due to excess alcohol consumption or other causes of
At present, no medication or surgical procedure has been approved for treating NAFLD ... Read More
Source: Johns Hopkins Bloomberg School of Public Health
To assess the knowledge of both type 2 diabetics and non-diabetics on diabetes, nutrition,
and exercise. Although type 2 diabetics should know more about their disease and its needs,
it is not expected they will know significantly more than the lay public.
Source: Johns Hopkins Bloomberg School of Public Health
Intervention study in malnourished adults to assess whether a nutritional supplement given
for 8 weeks in addition to the subject's usual diet improves body weight, body composition,
biochemical and immune parameters.
Source: Arkansas Children's Hospital Research Institute
The purpose of this study is to characterize physical growth, body composition, dietary
intake, neurobehavioral development, and brain function of infants and children fed mostly
breast-milk, milk-based formula or soy-based formula during their first year of life.
Children are followed from age 2 months to age 6 years.
The study hypothesizes that one form of food supplement to HIV-infected individuals in Haiti
(ready-to-use-supplementary food) will result in improved HIV, nutrition and quality of life
outcomes when compared to a second type of food supplement (corn-soy-blend) over the course
of 12 months of food supplementation.
In this study, an oral nutrition supplement has been developed that take into consideration:
the nutritional requirements, treatment side-effects and taste preferences of head and neck
cancer patients; the acceptance of a supplement when experiencing radiation therapy
side-effects; and the taste preferences of head and neck cancer patients which may affect
the supplement intake. We hope to increase dietary intake during the last 2 weeks of
radiation ... Read More
Source: National Nutrition and Food Technology Institute
The purpose of this study is to investigate the effects of curcumin supplement on metabolic
factors and hepatic fibrosis in nonalcoholic fatty liver patients with type 2 diabetes.
Subjects will participate in 3 month, two group, randomized intervention, where one group
(n=25) will take 1.5g/d curcumin and the other group (n=25) will take a placebo to compare
differences in outcomes between the two groups.
To compare two lipid emulsions in the long-term parenteral alimentation of patients with
AIDS in relation to: Clinical effectiveness. Effect on immunologic function. Effect on HIV
load as measured by p24 antigen levels. Effect on relative HIV infectivity.
Carbohydrate ingestion, in particular fructose, has been shown in a handful of previous
studies to elicit a thermic effect and increase core body temperature after ingestion.
Carbohydrate foods and supplements are commonly consumed prior to endurance running
competition, including situations where an athlete's ability to dissipate body heat is
compromised. Thus, there is some potential for pre-exercise carbohydrate ingestion to have a
deleterious effect on ... Read More
The purpose is to investigate the effect of sedentary screen time activities on food intake
and subjective appetite in 9- to 14-year old normal weight and overweight/obese girls. The
investigators hypothesize that pre-meal exposure to screen time activities for 45 minutes
increases subjective appetite and food intake at the next meal. Food intake will be measured
immediately following screen-time exposure, and subjective appetite measured throughout the
... Read More
The purpose of this study is to assess overall growth of preterm infants fed a reformulated
preterm infant formula during hospitalization. All study products meet levels of nutrients
for the infant population as specified in the Infant Formula Act and all subsequent
This clinical trial will evaluate the stool of infants fed one of two infant formulas, which
contain different types of proteins, or breast milk to determine if different proteins have
an effect on the type of bacteria that enters and lives in an infant's intestine early in
Children who recover from moderate acute malnutrition in Malawi remain at high risk for
relapse or death in the year following recovery. This cluster-randomized trial will evaluate
a package of affordable, safe, proven interventions specifically targeted to this population
of children in an attempt to decrease their risk of relapse or death following recovery from
moderate acute malnutrition. These children will be followed for a year following recovery
to ... Read More
The purpose of this research study is to determine if the diameter and flow of the superior
mesenteric artery in patients with aneurysmal subarachnoid hemorrhage undergoing
hypertensive therapy for cerebral artery vasospasm are effected enough to justify
withholding enteral nutrition.