In the First-line Antimetabolites as Steroid-sparing Treatment (FAST) Uveitis Trial, the
investigators propose to establish which immunosuppressive therapy, methotrexate or
mycophenolate mofetil, is more effective as a first-line, corticosteroid-sparing agent for
the treatment of non-infectious uveitis in a block-randomized, observer-masked, comparative
Introduction: Traumatic injuries to the outer covering of the eye (the cornea) are a common
emergency department complaint. They cause significant patient distress including pain, loss
of sleep and missed work days. There is currently no accepted, uniform approach to pain
management in this patient population. Emergency medicine and ophthalmology texts state that
prolonged use of medications that anesthetize the cornea is not recommended. Several recent
... Read More
This is a Phase II randomized, double-masked study comparing the safety and efficacy of
ATG003 (mecamylamine HCl) 1.0% and 0.3% ophthalmic solutions to placebo in patients with
neovascular ("wet") age-related macular degeneration (NV-AMD).
This study aims to assess if Lucentis injection applied into the eye is superior to
conventional treatment concerning the prevention of visual loss in patients having
clinically significant macular edema secondary to retinal vein occlusion
Acute anterior uveitis (AU) is a common reason for attendance at ophthalmic outpatient
clinics. The painfulness and the fear of a transient or even persistent loss of vision may
markedly reduce the individual's subjective well-being and pose a psychological burden.
This study will test the hypothesis that during an attack of AU the patient experiences a
marked reduction in psychological and physical well-being.
Prospective, hospital-based epidemiologic ... Read More
Source: The Eye Center and The Eye Foundation for Research in Ophthalmology
The main purpose of this study is to describe the optical coherence tomography (OCT)
findings in eyes with scleral inflammation and to differentiate cases with anterior
scleritis from those with episcleritis and normal controls.
Source: National Institute of Endocrinology and Diabetology, Slovakia
The aim of the study is to find out prevalence of diabetic macular edema (DME) in patients
with diabetes mellitus in Slovak Republic.The outcome of the project will be epidemiology
survey, prevalence of wet form of Diabetic Macular Edema in relation to duration of
diabetes, type of diabetes, treatment (insulin vs. OAD or combination) etc. and
identification of prognostic factors leading to development of DME.
To evaluate the effectiveness of both argon laser photocoagulation and aspirin therapy in
delaying or preventing progression of early diabetic retinopathy to more severe stages of
visual loss and blindness.
To help determine the best time to initiate photocoagulation treatment in diabetic
To monitor closely the effects of diabetes mellitus and of photocoagulation on visual
To produce natural history data that can be used ... Read More
This study investigates the hypothesis that ranibizumab injection given into the eye is an
efficacious and safe treatment option applied for swelling of the macula (site of sharp
vision) in diabetes.
The primary objective of this study was to investigate the efficacy of bromfenac sodium
ophthalmic solution 0.09% for treatment of post-operative ocular inflammation in subjects
who undergo cataract extraction and intraocular lens implantation. The secondary objective
was to investigate the safety and tolerability of the same.
The purpose of this study is to assess the influence of vitrectomy on changes in central
choroidea and comparing the results in imaging of the choroidea with two different OCT
This is a prospective, open, non-randomized, observational, MPG study This study will be
performed at the Department of Ophthalmology, Medical University of Vienna.
40 Patients who undergo vitrectomy will be included into this study. The investigation will
help to gain ... Read More
This post-market surveillance study is conducted in the European Economic Area where Argus
II has been CE certified for use in outer retinal degeneration patients. This study is being
conducted to monitor the use of Argus II in a larger population than available within
pre-market approval studies. Safety data will be monitored to ensure continued acceptability
of risks to study participants, and an attempt will be made to include all eligible and
willing ... Read More
The purpose of this study is to compare the safety & effectiveness of the two types of
cataract and glaucoma surgeries. Results from this study may improve the surgical and post
surgical management and long term management of patients with these conditions in the future