Metabolic syndrome consists of a group of co-occuring conditions that increase an
individual's risk of developing heart disease, stroke, and diabetes. The purpose of this
study is to evaluate the short-term effectiveness of chloroquine, a protein-activation
medication, at improving metabolic syndrome.
The metabolic syndrome is a collection of related risk factors that predispose to the
development of type 2 diabetes Mellitus and cardiovascular disease. The investigators will
examine the hypothesis that the metabolic and genomic characteristics of patients with
metabolic syndrome and/or diabetes that are at risk for developing complications differ from
each other and can be detected using specific biomarkers in blood or in the exhaled breath.
Early ... Read More
Source: Grigore T. Popa University of Medicine and Pharmacy
- assessment of renal artery stenosis incidence in consecutive AMI patients included in
the Romanian National Programme of Primary Percutaneous Revascularisation;
- generating a cardio-renal-metabolic profile in patients with renal atherosclerotic
- creating a local registry (based on European CARDS percutaneous interventional
registries) which also includes renal, metabolic and vascular data;
- ... Read More
An educational intervention in the General Medicine Clinic aimed at both primary care
providers (PCPs) and their patients with metabolic syndrome/pre-diabetes (MetSyn/PDM).
Improving PCPs ability to detect and manage MetSyn/PDM, as measured by the increased
incorporation of MetSyn/PDM into PCPs care plan, and increasing patients' awareness of
healthy lifestyle behaviors results in positive patient health behaviors and outcomes.
The purpose of this research study is to examine whether sugar-replacement sweeteners that
are currently on the market (ex. Sucralose, which is in Splenda) change how well the body
works to control blood sugar.
Five factor consisting of Metabolic syndrome is closely linked by insulin resistance. Until
now, several studies have been performed about effects of Korea red ginseng on hypertension,
diabetes, and hyperlipidemia, but not metabolic syndrome.
The investigators hypothesize that Korean red ginseng could improve each constituents of
metabolic syndrome, arterial stiffness, and inflammatory markers.
The aim of this study is to determine effects of Korean red ... Read More
Source: USDA Beltsville Human Nutrition Research Center
The objective is to develop a new metabolic flexibility biomarker, which has application in
the study of changes diet and exercise on fuel management in humans. The new biomarker
involves the characterization of an individual's metabolic flexibility utilizing room
calorimeters rather than the current method, which is based on glucose clamp data. It is
hypothesized that this new metabolic flexibility method will be a useful and noninvasive
biomarker for ... Read More
The metabolic syndrome is a highly prevalent disorder, which causes atherosclerotic
cardiovascular disease and is closely associated with insulin resistance. The alteration of
the secretion of adipocytokines from accumulated visceral adipose tissue in the obese
induces insulin resistance. The purpose of this study is to identify gene polymorphisms that
confer susceptibility to the metabolic syndrome and to make up a new health guidance program
based on ... Read More
This is a randomized controlled Trial to evaluate effect of a culturally and linguistically
tailored, telephone-delivered behavioral intervention on adherence to recommended assessment
and treatment of sleep apnea in Blacks with Metabolic Syndrome. The investigators believe
low awareness of Sleep Apnea and the risk it imposes to an individual health plays an
important role in underdiagnosis and low adherence to treatment among Blacks. Hence,
culturally and ... Read More
The aim of this study is to assess the frequency of metabolic syndrome in Down syndrome
patients because the prevalence of diabetes mellitus and obesity is higher in individuals
with Down syndrome than in the general population.
This is a 3-arm, randomized, double-blind, double-dummy, and controlled clinical study over
6 months of treatment to evaluate the metabolic and clinical efficacy as well as the safety
of DLBS3233 alone, metformin and combination of both, in improving metabolic and
A growing number of people in this country are overweight or obese. This is concerning as
increasing weight has been shown to increase the risk of developing heart failure. However,
there is also research to suggest that in people who already have heart failure, heavier
people live longer. So, how does being overweight put a person at risk for heart failure,
but once they have heart failure, protect them? There is no clear explanation for this
... Read More
Heart failure is a condition where the heart does not pump enough blood to the rest of the
body. People with heart failure may have another condition called the "metabolic syndrome"(
having excess fat in the belly, high blood pressure, high fat in the blood, low level of
good cholesterol and high blood sugar). People who have both heart failure and the metabolic
syndrome often see many doctors. A new clinic has been formed at Ben Taub General Hospital
that ... Read More
Chloride-rich isotonic crystalloid solutions have been shown to exert electrolyte imbalance
and metabolic acidosis in critically ill patients. The aim of this investigation is to
compare the influence of 0.9% saline and plasmalyte solution on acid-base balance and
electrolytes in healthy patients undergoing major spine surgeries.
We, the investigators at National Taiwan University Hospital, want to compare patients'
islet cell function, insulin sensitivity and risk of chronic complications with normal
subjects. Moreover, we want to examine whether they are at a higher risk of having metabolic
syndrome and to answer whether we should screen the phenotypes of metabolic syndrome in
impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) patients. Then, we want
to examine the ... Read More