This randomized phase III trial studies how well caspofungin acetate works compared to
fluconazole or voriconazole in preventing fungal infections in patients following donor stem
cell transplant. Caspofungin acetate, fluconazole, and voriconazole may be effective in
preventing fungal infections in patients following donor stem cell transplant. It is not yet
known whether caspofungin acetate is more effective than fluconazole or voriconazole in
preventing ... Read More
The objective of this study is to investigate the effects of physical training in patients
with type 2 diabetes during treatment with the GLP-1 receptor agonist liraglutide (Victoza®)
in a 16-weeks double-blinded, randomized placebo-controlled clinical trial.
Hypothesis: Physical training leads to better metabolic control in type 2 diabetic patients
when training is combined with liraglutide (Victoza®) treatment.
In the present study the investigators are trying to evaluate the effect of Murraya koenigii
leaves, Punica granatum and Curcuma which is administered to the patients in a combined form
as tea. This study will help to evaluate the effect of these preparations scientifically in
improving the IBS symptoms.
The purpose of this study is to investigate the effects of mexiletine treatment for 6 months
on ambulation, myotonia, muscle function and strength, pain, gastrointestinal functioning,
cardiac conduction, and quality of life in myotonic dystrophy type 1 (DM1).
Dolutegravir (DTG, GSK1349572) is an integrase inhibitor currently in Phase 3 clinical
trials for the treatment of human immunodeficiency virus (HIV) infection. A granule
formulation has been developed as an alternative to the current tablet formulation for
administration in pediatric populations.
This is a single-center, randomized, open-label, 5-way crossover study in healthy adult
subjects. The study will evaluate the relative bioavailability of a 50 mg ... Read More
The purpose for this study is to demonstrate the safety and immunogenicity of two doses of
Menactra® administered between 12 and 18 months of age and concomitantly with routine
immunization with two different provincial schedule
- To describe the immunogenicity of Menactra® administered concomitantly with routine
immunizations at 12 and 18 months in naïve or Menjugate-primed (MenC-primed) infants
(measured by serum ... Read More
Currently, in the U.S., 1 in 3 males and 2 in 5 females born after 2000 are expected to
develop diabetes during his or her lifetime. Research has demonstrated that control of blood
glucose (BG) reduces the complications of diabetes. As a result, almost half of Americans
diagnosed with diabetes, are prescribed finger-stick glucose meters to monitor their BG. The
value of this approach is known to be limited by a high rate of patient non-compliance with
BG ... Read More
Patients have a type of lymph gland disease called Hodgkin or non-Hodgkin lymphoma which has
come back, or may come back, or has not gone away after treatment, including the standard
treatment known for these diseases. This a research study using special immune system cells
called tumor associated antigen (TAA)-specific cytotoxic T lymphocytes, a new experimental
This sort of therapy has been used previously to treat Hodgkin or non-Hodgkin ... Read More
This open-label, multicenter study will evaluate the safety and efficacy of RO5185426 in
patients with BRAF V600 mutation-positive, surgically incurable and unresectable stage IIIC
or IV metastatic melanoma. Eligible patients will receive RO5185426 (960 mg twice daily
orally) until disease progression or unacceptable toxicity occurs, with a safety follow-up
of 24 months after discontinuation of the study drug.
The primary objective of this clinical study is to determine whether the Innova Stent System
shows acceptable performance in long-term (12-month) safety rates and vessel patency when
treating femoropopliteal lesions.
VEGF Trap-Eye will be tested for safety and efficacy in patients with vision loss due to
choroidal neovascularization secondary to pathologic myopia. This will be a
placebo-controlled trial. 3 out of 4 patients will receive an injection of VEGF Trap-Eye
into the affected eye (and repeated injections if required), and 1 out of 4 patients will
receive a sham injection requiring no needle stick, but making the patient unaware of
whether or not he received ... Read More
Double blind, prospective, randomized, placebo-controlled Safety and Efficacy trial of ADRCs
delivered via the intracoronary route in the treatment of patients with ST-elevation acute
myocardial infarction (STEMI).
The objective of this study is to investigate the relative contributions of nicotine
replacement and sensorimotor replacement (i.e., smoking denicotinized cigarettes) on
abstinence-induced smoking urges, withdrawal-related negative affect, psychiatric symptoms,
cognitive task performance and smoking behavior in smokers with schizophrenia and
Source: Taipei Medical University WanFang Hospital
Portfolios are the records of learning process, providing evidences of experiential
learning. It can be a valuable tool not only for understanding the learning process but also
for evaluating the accomplishment. Portfolios promote learners to reflecting, thinking,
improving in learning as well as achieving learning goals. It has been widely applied in
medical education. The goals of resident training outcomes in Wan-Fang Hospital are the
ACGME six core ... Read More
The purpose of the study is to assess the efficacy and safety of XP21279/Carbidopa in
comparison to Sinemet as well as evaluate the pharmacokinetics (PK) of levodopa after
administration of XP21279/Carbidopa and Sinemet and to explore exposure-response
relationships in a subset of subjects.
Our hypothesis is that the Waters Medical® pulsatile perfusion machine (RM 3) is a way to
improve delayed graft function (DGF) in marginal grafts, and some perfusion profiles (flow,
pressure, resistance index, venous effluent pH) are correlated with better recovery of renal
function (without dialysis during the first week after transplant).
Observation or Investigation Method Used :
The study is multicenter, prospective, open, controlled and ... Read More
The study consists in only one treatment group, which will receive the first-line therapy
for the disease - standard radiotherapy and a 150 mg/m2 dose of the investigational product