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Clinical Trials: Nutrition & Dietetics


Source: Shanghai Zhongshan Hospital
Patients with mechanical ventilation are in risk of malnutrition, which could lead to worse outcome. According to guidelines released from authority organizations, enteral nutrition (EN) should be prior approach for critically ill patients. However, initiation and delivery of EN during the early period of ICU admission are frequently hampered, which results in underfeeding. The investigators speculate whether an intensive enteral nutrition strategy could ... Read More
Last Updated: 09 Nov 2016
Source: McGill University Health Center
A prospective, randomized and controlled study is proposed to establish whether an enteral nutrition support regimen based on pressurized whey protein and glucose improves the postoperative utilization of amino acid substrates compared to a drink based on glucose alone. The kinetics of protein metabolism (protein breakdown, protein synthesis and amino acid oxidation) will be investigated using stable isotope methodology before and after surgery in patients ... Read More
Last Updated: 11 Jan 2011
Source: Amarnath, Rathna, M.D.
This pilot study seeks to demonstrate the efficacy of an intravenous lipid preparation high in omega-3 fatty acids (Omegaven) in the treatment of cholestasis in parenteral nutrition dependent patients with short gut syndrome. Read More
Last Updated: 28 Nov 2012
Source: Nestlé
To assess the effect of consumption of an oral nutrition supplement on Arginine, a blood marker of nutritional intake Read More
Last Updated: 13 Jun 2016
Source: State Key Laboratory of Cancer Biology
Colorectal cancer incidence is increasing at an alarming rate in China. Recent reports concluded nutrition status and lifestyle factors were associated with colorectal cancer risk, however, the influence of nutrition and lifestyle factors on cancer outcome in colorectal cancer survivors is largely unknown.The investigators will explore the impact of nutrition status, life style, dietary pattern, obesity, physical activity, depression, diabetes, aspirin use ... Read More
Last Updated: 29 Oct 2014
Source: Centre Hospitalier Universitaire de Besancon
In malnourished patients in the palliative phase of cancer, the question is raised of the relevance of implementing artificial nutritional assistance instead of oral feeding when this is possible. Medical prescription and implementation of artificial nutrition at this stage of the illness seem less governed by data acquired by science than by subjective reasons (related to beliefs, to a cultural or religious tradition, to the symbolic role of eating, to the ... Read More
Last Updated: 02 Aug 2016
Source: University Hospital, Clermont-Ferrand
Myeloablative allogeneic hematopoetic stem cell transplantation (AHSCT) are prone to frequent secondary malnutrition to metabolic and digestive troubles due to conditioning regimen, treatments (antibiotics, immunosuppressive therapy…) and graft complications (graft versus host disease). In the absence of appropriate nutritional support, myeloablative conditioning lead to a rapid serious denutrition. But, it is known as negative independent prognostic factor ... Read More
Last Updated: 27 Jul 2016
Source: Yale University
The goal of the study is to determine if parenteral nutrition-associated cholestasis (PNAC) is related to the amount of parenteral (intravenous) fat administered to premature babies until full enteral nutrition is achieved. Read More
Last Updated: 26 Oct 2014
Source: IRCCS Policlinico S. Matteo
Although it is demonstrated that nutritional support can improve clinical outcomes, the literature shows that approximately 50% of cancer patients are not able to meet their estimated energy requirements. Recent clinical studies suggest that a supplementary support for parenteral nutrition (PN) could significantly help to improve the nutritional status of malnourished cancer patients. International guidelines recommend the use of PN in malnourished, ... Read More
Last Updated: 10 Jul 2016
Source: Oslo University Hospital
This is a randomized, double-blind trial looking at how nutrition intake is associated with labor progress and complications. Read More
Last Updated: 02 Jul 2011
Source: University Hospital, Geneva
Rationale: Enteral nutrition (EN) in the intensive care (ICU) patients is recommended as a standard of care. However, EN alone is often associated with insufficient energy intakes and increased complication rates. Recently the investigators proposed to decrease this deficit by combining EN and supplemental parenteral nutrition (SPN) whenever EN is insufficient (< 60% of their predicted energy needs) at day 3 after admission in the ICU. Objective: This study ... Read More
Last Updated: 17 Apr 2013
Source: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
The purpose of the study is to determine the tolerance on lipid metabolism and the safety of short-term parenteral nutrition as compared to enteral nutrition in critically ill patients with liver failure. Read More
Last Updated: 01 Sep 2009
Source: Children's Hospital Los Angeles
This study examines the hypothesis that administering intravenous fish oil, in lieu of intravenous soybean oil, can ameliorate the progression of PN-associated cholestatic liver disease in pediatric patients with elevated direct bilirubin requiring PN for more than 30 days. Read More
Last Updated: 03 Aug 2016
Source: Advocate Health Care
This is an expanded access protocol for use of intravenous fish oil infusion, Omegaven, in infants and children with parenteral nutrition associated liver disease (PNALD) to decrease elevated liver enzymes and direct bilirubin. This study aims to describe the response of PNALD after use of Omegaven by normalization of serum levels of liver enzymes and bilirubin. Read More
Last Updated: 06 Oct 2016
Source: Thai Red Cross AIDS Research Centre
To reassess nutritional status of HIV-infected Thai children living in the family style community after receiving nutrition support program for 6 months. Read More
Last Updated: 05 Nov 2009
Source: Centre Hospitalier Universitaire Vaudois
Having previously demonstrated that supplemental parenteral nutrition to complete an insufficient enteral nutrition (EN) between D4 and D8 improves outcome after critical illness, by reducing infectious complications, the present trial aims at investigating the underlying carbohydrate and protein metabolism changes, as well as the immune and inflammatory modulations associated with this improvement. Read More
Last Updated: 17 Feb 2016
Source: German Institute of Human Nutrition
We investigate the impact of taste receptors (sweet, bitter and umami) on human metabolism. There ist growing evidence, that components of the taste signalling system, including the taste receptor proteins , have important functions in the regulation of metabolic parameters in non-gustatory tissues. Read More
Last Updated: 17 Mar 2015
Source: University of New Mexico
This study will determine if an education program about hygiene and child feeding practices, taught by local village community health workers, will improve child growth and decrease the prevalence of childhood malnutrition in a rural region of Kenya. Read More
Last Updated: 03 Feb 2015
Source: Northwestern University
In this study, the investigators conducted research among HIV-infected and -uninfected pregnant and lactating women to understand the potential role and importance of food insecurity on participant physical and psychosocial health and nutrition. Read More
Last Updated: 21 Nov 2016
Source: Nestlé
This will be a randomized, cross-over study of two oral nutrition supplements in individuals with Type 2 Diabetes. Read More
Last Updated: 19 Nov 2015