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Source: Centre hospitalier de l'Université de Montréal (CHUM)
The purpose of this study is to assess the quality of postoperative pain management in a Canadian teaching hospital following thoracic surgery. Hypothesis: Postoperative pain management following thoracotomy or thoracoscopy is still suboptimal despite the evidence that adequate pain relief improves outcome. Read More
Last Updated: 11 Sep 2013
Source: University of Basel
To investigate the effects of the calcimimetic agent cinacalcet on cognitive functions in healthy humans. Read More
Last Updated: 01 Oct 2012
Source: University of Michigan
More than one in three US women suffers from the distressing, embarrassing, and often unreported problem of urinary incontinence (UI). UI severity increases with age and the financial cost exceeds $19 billion per year . The Adult Conservative Management Committee of the 2008 International Consultation on Incontinence concluded that pelvic floor muscle training (PFMT) should be offered as first line therapy to all women with stress, urge, or mixed UI; and ... Read More
Last Updated: 09 May 2016
Source: GlaxoSmithKline
This is a four-week, Phase IIa, randomized, active-controlled, parallel-group, multi-center study to evaluate the safety, efficacy and pharmacokinetics of switching subjects from stable rhEPO to GSK1278863 in approximately 68 hemodialysis-dependent subjects with anemia associated with chronic kidney disease. The study consists of a screening phase of 2 weeks, a 4-week treatment phase and a 2-week follow-up phase. The range of Hgb values for study eligibility ... Read More
Last Updated: 26 Jan 2017
Source: Biosense Webster, Inc.
The objective of this study is to determine whether early radiofrequency (RF) ablation treatment, using the CARTO® 3 or CARTO® XP System, and THERMOCOOL® Catheter Family (including THERMOCOOL® SF or THERMOCOOL® SMARTTOUCH™) in subjects with paroxysmal atrial fibrillation (PAF), delays progression of atrial fibrillation (AF) compared with drug therapy (either rate or rhythm control) using current AF management guidelines. Read More
Last Updated: 17 Jan 2017
Source: Samuel Lunenfeld Research Institute, Mount Sinai Hospital
There has been very little investigation into the management of pain from 2nd trimester termination of pregnancy or unexpected fetal loss. The standard of practice in North America is usually intravenous patient controlled analgesia (IV PCA), using a narcotic wuch as fentanyl. The goal of this study is to compare the quality of recovery after termination of pregnancy using fentanyl IV PCA or patient controlled epidural analgesia (PCEA), a standard of care ... Read More
Last Updated: 08 Oct 2014
Source: Dana-Farber Cancer Institute
This research study is a Phase II clinical trial. Phase II trials test the effectiveness of an investigational drug to learn whether the drug works in treating a specific cancer. "Investigational" means that drug is still being studied and that research doctors are trying to find out more about it-such as the safest dose to use, the side effects it may cause, and if the drug is effective for treating different types of cancer. It also means that the FDA has ... Read More
Last Updated: 24 Nov 2015
Source: Dana-Farber Cancer Institute
STA9090 is a drug which inactivates or blocks the work of a protein called Heat Shock Protein 90 or HSP90. HSP90 is a protein that helps some molecules inside your cells to have the right shape. By stopping HSP90's activity, those molecules never get to have the right structure of be functional and they are destroyed. The investigators believe that if they stop the activity of HSP90, the rapidly dividing cells that are in your tumor(s) may slow down. In this ... Read More
Last Updated: 15 Nov 2016
Source: University Hospital, Basel, Switzerland
Background: Poor wound healing and the development of surgical site infection (SSI) continue to occur and remain a significant cause of disability among operated patients. In spite of the substantial advances in our understanding of the epidemiology, pathogenesis and prevention it remains one of the most common complications in conventional abdominal surgery with an incidence in the literature between 4% and 17%. As it is known that surgical sutures ... Read More
Last Updated: 16 Mar 2015
Source: Institut Paoli-Calmettes
The aim of this study is to test the additional value of neoadjuvant chemotherapy to the standard treatment for resectable pancreatic cancer (surgery + adjuvant chemotherapy). This study will be performed in compliance with the study protocol, GCP (good clinical practice) and the applicable regulatory requirements. Read More
Last Updated: 18 Mar 2015
Source: G&E Herbal Biotechnology Co., LTD
This Phase II study is to evaluate the efficacy of SR-T100 gel with 2.3% of SM in Solanum undatum plant extract in patient with Actinic Keratosis (AK). Read More
Last Updated: 16 Feb 2016
Source: University of Florida
The fact that dental caries remains a major public health problem mandates that oral-health researchers explore new strategies for assessment of caries risk, as well as for caries prevention and management. Dental caries occurs when acids produced by bacterial glycolysis of dietary carbohydrates causes demineralization of the tooth enamel. A major focus of caries research has been on identifying and characterizing acid-generating bacteria and the mechanisms ... Read More
Last Updated: 08 Aug 2016
Source: Shandong University
The project was undertaking by Qilu Hospital of Shandong University and other well-known hospitals in China. Aims at evaluating efficacy and safety of rhTPO in management of ITP in pregnancy. Read More
Last Updated: 17 Apr 2016
Source: Hyundai Pharmaceutical Co., LTD.
Chronic renal failure is a syndrome that renal function is decreased, and the patient number is increasing. In addition, patients on dialysis have also increased. Depending on the chronic renal failure aggravated, the deterioration of life caused by the conduct of dialysis patients is caused. In addition, a problem in dialysis treatment is ongoing economic burden surface to increase the life of the patient and family. A solution to this problem is, or stops ... Read More
Last Updated: 25 Feb 2015
Source: Memorial Sloan Kettering Cancer Center
The purpose of this study is to use a new type of scan, called 68Ga-DOTATOC PET/CT scan, instead of OctreoScan, the standard scan, to diagnose, monitor and manage your tumor. 68Ga-DOTATOC is an improved imaging agent being routinely used in many centers outside the USA, with better tumor detection than with OctreoScan. Read More
Last Updated: 31 Oct 2016
Source: Samsun Education and Research Hospital
The current guidelines still recommend emergent PCI of the culprit lesion and state that primary PCI should be limited to the culprit vessel with the exception of cardiogenic shock and persistent ischaemia after PCI of the supposed culprit lesion. This recommendation is based on a high number of studies. However, several studies are present about the safety and efficacy of non-culprit vessel PCI during acute MI. Nowadays, the debate is increasingly going on ... Read More
Last Updated: 03 Feb 2015
Source: St. Mary's Research Center, Canada
This study is focused on comparing patients' pain scores on a visual analogue scale (VAS) and the difference in analgesics use post-operatively (with the same prescription defining only the maximum frequency) between lidocaine with epinephrine & bupivacaine with epinephrine as local anesthetics in wide-awake hand surgery. The investigators' hypothesis states that a longer acting local anesthetic agent (bupivacaine) would be able to provide better ... Read More
Last Updated: 08 Dec 2014
Source: Norwegian University of Science and Technology
The aim of the study is to evaluate whether walking capacity in patients with intermittent claudication is improved more by home-based 5+ exercise training than by current recommendations of daily walking. The study will elucidate if such a potential effect is dependent on changes in mitochondrial respiratory capacity, blood flow or both. Read More
Last Updated: 03 Aug 2016
Source: Cornell University
Examining the effect of daily self-weighing on the ability of student to prevent from gaining weight during their four years at Cornell. Read More
Last Updated: 23 Nov 2014
Source: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
To evaluate the exercise tolerance during pregnancy and after thanks the 6MWT Read More
Last Updated: 17 Nov 2014