A Research About Nutrition Impact for Local Advanced Nasopharyngeal Carcinoma Patients

NCT ID: NCT02948699


Title
A Prospective, Randomized Controlled Open Research About the Impact of Nutritional Support on the Radiation Tolerance and Clinical Outcomes for Local Advanced Nasopharyngeal Carcinoma Patients
Purpose
The chemo-radiotherapy for the local advanced nasopharyngeal carcinoma patients will induce the mucosal ulcer and damage salivary glands. Consequently, it can disturb the nutrition conditions and clinical outcomes of patients. This research tries to evaluate the nutrition status at the baseline, before and after radiotherapy, during the follow-up by the body mass index, hematological indexes, immunological indexes, and nutrition questionnaires including PG-SGA and NRS 2002. Through the evaluation of two different nutritional interventions, the investigators aim to find an optimized assessment model and the best nutrition support patterns.
Details
All nasopharyngeal patients received radical treatment including neo-adjuvant chemotherapy and concurrent chemo-radiotherapy. At the beginning, the investigators assign patient to experimental and control groups randomly. Patients in experimental group received standard nutritional support by adding NUTRISON. Control patients will give conventional nutritional guidance. The investigators collected all the nutritional indexed at first visit, before and after radiotherapy, 1, 3, 6, 9, 12 months after radiotherapy. All these data will be set into statistical software to produce an optimized model for clinical practice.
Conditions
Malignant Neoplasm of Nasopharynx
Keywords
nasopharyngeal carcinoma, intensity-modulated radiotherapy, nutrition support, nutrition assessment
Source
Zhejiang Cancer Hospital
Sponsors
Zhejiang Cancer Hospital
Status
Not yet recruiting
Acronym
Last Updated
26 Oct 2016
URL
Official Link
Locations
China