Diabetes Nutrition Algorithm - Prediabetes

NCT ID: NCT02609243


Title
Diabetes Nutrition Algorithm - Prediabetes (Dietary Strategies in the Prevention of Diabetes Mellitus Type 2 in a High-risk Cohort)
Purpose
Prediabetes, defined by either impaired fasting glucose and/or impaired glucose tolerance, is a known high-risk condition predisposing to future diabetes mellitus type 2. Strategies to prevent progression from prediabetes to diabetes have been widely studied, however, without striking long-term effects of any kind of intervention (pharmacological, behavioral...). The investigators therefore investigate certain nutritional approaches concerning nutrient content and favorable food components, targeting metabolic improvement.
Details
Prediabetes, defined by either impaired fasting glucose and/or impaired glucose tolerance, is a known high-risk condition predisposing to future diabetes mellitus type 2. Strategies to prevent progression from prediabetes to diabetes have been widely studied, however, without striking long-term effects of any kind of intervention (pharmacological, behavioral...). The investigators therefore investigate certain nutritional approaches concerning nutrient content and favorable food components, targeting metabolic improvement. The main comparison will assess differences in metabolic outcome due to low-carb or low-fat dietary intervention in short- and long-term design. Additionally, the role of PUFA will be assessed during long-term intervention to achieve better maintenance of metabolic improvements from the first study phase.
Conditions
Prediabetes, Diabetes Mellitus Type 2, Obesity, NAFLD, Dyslipoproteinemia
Keywords
prediabetes, diabetes mellitus type 2, obesity, NAFLD, dyslipoproteinemia
Source
German Institute of Human Nutrition
Sponsors
German Institute of Human Nutrition, German Diabetes Center
Status
Recruiting
Acronym
DiNA-P
Last Updated
20 Nov 2016
URL
Official Link
Locations
Germany