Effect of Regulated Pleural Pressure on Air Leak and Fluid Drainage Following Pulmonary Resections: A Multicenter Randomized Trial

NCT ID: NCT02002273


Title
The Effect of Regulated Pleural Pressure on The Duration of Air Leak and Fluid Drainage Following Pulmonary Anatomic Resections: A Multicenter Randomized Trial
Purpose
The objective of this randomized study is to compare the effect of two controlled chest tube protocols on the duration of air leak and fluid drainage following pulmonary lobectomy or segmentectomy by using an electronic regulated chest drainage system (Thopaz). Previous studies have suggested that the amount of negative pressure used at the level of the chest drainage device may affect the duration of air leak, but the results have been inconsistent, however as revealed in more recent studies understanding of the physics of chest drainage devices may have been confounded by lack of regulation of the pleural pressure. In addition, experimental studies have shown that fluid drainage may be affected by the degree of negative pleural pressure applied.
Details
Conditions
Lung Cancer
Keywords
Source
Ospedali Riuniti Ancona
Sponsors
Ospedali Riuniti Ancona, The Leeds Teaching Hospitals NHS Trust, Yale University, The University of Hong Kong
Status
Withdrawn
Acronym
Last Updated
27 Mar 2016
URL
Official Link
Locations
Italy