Early Goal-Directed Nutrition in ICU Patients - EAT-ICU Trial

NCT ID: NCT01372176


Title
Early Goal-Directed Nutrition in ICU Patients - EAT-ICU Trial
Purpose
An increasing number of patients survive critical illness and intensive care, but describe having impaired physical function several years after discharge as a consequence of extensive loss of muscle mass. Reasons for loss of muscle mass and physical function are multiple, but insufficient nutrition is likely to contribute. This randomised trial will investigate the effect of an optimised nutrition therapy during intensive care, on short term clinical outcome and physical quality of life. We hypothesise, that early nutritional therapy, directed towards patient-specific goals for energy and protein requirements, will improve both short- and long-term outcomes.
Details
Conditions
Critical Illness, Intensive Care (ICU) Myopathy, Muscle Wasting, Loss of Physical Function, Mechanical Ventilation
Keywords
Intensive care unit, Critical illness, Mortality, Reduced quality of life, Loss of lean body mass, Loss of physical function, Optimised nutritional support, Early initiation of nutrition, Indirect calorimetry
Source
Rigshospitalet, Denmark
Sponsors
Rigshospitalet, Denmark, University of Copenhagen, Fresenius Kabi, The European Society for Clinical Nutrition and Metabolism (ESPEN)
Status
Completed
Acronym
EAT-ICU
Last Updated
03 Jan 2017
URL
Official Link
Locations
Denmark