Azathioprine & Allopurinol in Inflammatory Bowel Disease Patients

NCT ID: NCT00849368


Title
Dose-effect Relationship Between Allopurinol, Azathioprine and 6-thioguanine Nucleotide Levels (6-TGN) in Inflammatory Bowel Disease Patients.
Purpose
Main Study Objectives: The study is conducted to - evaluate the minimal allopurinol and azathioprine doses that, in combination, produce therapeutic 6-TGN levels - evaluate the safety and tolerability of the different allopurinol/azathioprine dose levels - assess if concomitant allopurinol affects TPMT activity - assess the clinical efficacy of concomitant allopurinol-azathioprine therapy in the included patients
Details
Conditions
Inflammatory Bowel Disease
Keywords
Source
University of Zurich
Sponsors
University of Zurich
Status
Completed
Acronym
Last Updated
05 Feb 2012
URL
Official Link
Locations
Switzerland