Timing of Target Enteral Feeding in the Mechanically Ventilated Patient

NCT ID: NCT00252616


Title
Phase III Study of Early vs. Delayed Goal Enteral Nutrition in Mechanically Ventilated Patients
Purpose
This study tests the hypothesis that initial trophic enteral feedings will increase the time alive and free of mechanical ventilation as compared to initial goal enteral feedings in patients who are mechanically ventilated.
Details
Mechanically ventilated patients, within 48 hours of initiating mechanical ventilation, are randomized in a 1:1 fashion to receive trophic enteral feedings for 96 hours followed by advancement to goal feeding rates or initial advancement to goal feeding rates. Primary endpoints are ventilator free days, ICU-free days, gastrointestinal intolerances, development of nosocomial infections, and mortality.
Conditions
Acute Respiratory Failure
Keywords
Mechanical ventilation, acute respiratory failure, early nutrition
Source
Vanderbilt University
Sponsors
Vanderbilt University, National Institutes of Health (NIH)
Status
Completed
Acronym
Last Updated
15 Dec 2013
URL
Official Link
Locations
United States